The biological diversity of the unicellular bacteria—whether assessed by shape, food,
metabolism, or ecological niche—surely rivals (if not exceeds) that of the multicellular …

As bacteria proliferate, DNA replication, chromosome segregation, cell wall synthesis, and
cytokinesis occur concomitantly and need to be tightly regulated and coordinated. Although …

Bacterial cell wall biosynthesis is the target of many important antibiotics. Its spatiotemporal
organization is closely coordinated with cell division. However, the role of peptidoglycan …

Staphylococcus aureus is a Gram-positive pathogen responsible for antibiotic-resistant
infections. To identify vulnerabilities in cell envelope biogenesis that may overcome …

The bacterial pathogen, Staphylococcus aureus, grows by dividing in two alternating
orthogonal planes. How these cell division planes are positioned correctly is not known …

Cell division in Streptococcus pneumoniae (pneumococcus) is performed and regulated by
a protein complex consisting of at least 14 different protein elements; known as the …

Ovoid-shaped bacteria, such as Streptococcus pneumoniae (pneumococcus), have two
spatially separated peptidoglycan (PG) synthase nanomachines that locate zonally to the …

Bacterial cell division is a complex process requiring the coordination of multiple
components to allow the appropriate spatial and temporal control of septum formation and …

For decades, cells of the Gram-positive bacterial pathogen Staphylococcus aureus were
thought to lack a dedicated elongation machinery. However, S. aureus cells were recently …

Bacterial cell growth and division require temporal and spatial coordination of multiple
processes to ensure viability and morphogenesis. These mechanisms both determine and …