The discovery, commercialization, and routine administration of antimicrobial compounds to
treat infections revolutionized modern medicine and changed the therapeutic paradigm …

Respiratory mutants, both naturally occurring and genetically constructed, have taught us
about the importance of metabolism in influencing virulence factor production, persistence …

In Staphylococcus aureus, hundreds of small regulatory or small RNAs (sRNAs) have been
identified, yet this class of molecule remains poorly understood and severely understudied …

The success of Staphylococcus aureus, as both a human and animal pathogen, stems from
its ability to rapidly adapt to a wide spectrum of environmental conditions. Two-component …

Numerous factors have, to date, been identified as playing a role in the regulation of Agr
activity in Staphylococcus aureus, including transcription factors, antisense RNAs, and host …

Lactococcus cremoris and L. lactis are well known for their occurrence and applications in
dairy fermentations, but their niche extends to a range of natural and food production …

Staphylococcus aureus is a major human pathogen that causes infection in a wide variety of
sites within the human body. Its ability to adapt to the human host and to produce a …

Pseudomonas aeruginosa is a major pathogen in burn wound infections. We present one of
the first reports of small-colony variant (SCV) emergence of P. aeruginosa, taken from a …

Protein prenylation is one of the most important posttranslational modifications of proteins.
Prenylated proteins play important roles in different developmental processes as well as …

Farnesyltransferase inhibitors (FTIs) are focus for the treatment of several diseases,
particularly in the field of cancer therapy. Their potential, however, goes even further, as a …