The intricacy of diseases, shaped by intrinsic processes like immune system exhaustion and
hyperactivation, highlights the potential of immune renormalization as a promising strategy …

As a nontraditional T-cell subgroup, γδT cells have gained popularity in the field of
immunotherapy in recent years. They have extraordinary antitumor potential and prospects …

PURPOSE AND APPROPRIATE SAMPLE TYPES This 40‐color flow cytometry‐based panel
was developed for in‐depth immunophenotyping of the major cell subsets present in human …

Clinical responses to checkpoint inhibitors used for cancer immunotherapy seemingly
require the presence of αβT cells that recognize tumour neoantigens, and are therefore …

These guidelines are a consensus work of a considerable number of members of the
immunology and flow cytometry community. They provide the theory and key practical …

The third edition of Flow Cytometry Guidelines provides the key aspects to consider when
performing flow cytometry experiments and includes comprehensive sections describing …

Many countries are facing the aging of their population, and many more will face a similar
obstacle in the near future, which could be a burden to many healthcare systems. Increased …

Gamma delta (γδ) T cells reside within human tissues including tumors, but their function in
mediating antitumor responses to immune checkpoint inhibition is unknown. Here we show …

Vδ2+ T cells form the predominant human γδ T-cell population in peripheral blood and
mediate T-cell receptor (TCR)-dependent anti-microbial and anti-tumour immunity. Here we …

The unique cytokine signature of COVID-19 might provide clues to disease mechanisms and
possible future therapies. Here, we propose a pathogenic model in which the alarmin …