Rheumatic heart valve disease pathophysiology and underlying mechanisms

LSA Passos, MCP Nunes, E Aikawa - Frontiers in Cardiovascular …, 2021 - frontiersin.org
Rheumatic heart valve disease (RHVD) is a post-infectious sequel of acute rheumatic fever
resulting from an abnormal immune response to a streptococcal pharyngitis that triggers …

Risk factors for acute rheumatic fever: literature review and protocol for a case-control study in New Zealand

MG Baker, J Gurney, J Oliver, NJ Moreland… - International journal of …, 2019 - mdpi.com
Acute rheumatic fever (ARF) and its sequela, rheumatic heart disease (RHD), have largely
disappeared from high-income countries. However, in New Zealand (NZ), rates remain …

Preceding group A streptococcus skin and throat infections are individually associated with acute rheumatic fever: evidence from New Zealand

J Oliver, J Bennett, S Thomas, J Zhang, N Pierse… - BMJ Global …, 2021 - gh.bmj.com
Introduction Acute rheumatic fever (ARF) is usually considered a consequence of group A
streptococcus (GAS) pharyngitis, with GAS skin infections not considered a major trigger …

Acute rheumatic fever and rheumatic heart disease: highlighting the role of group A Streptococcus in the global burden of cardiovascular disease

T Auala, BLG Zavale, AÇ Mbakwem, AO Mocumbi - Pathogens, 2022 - mdpi.com
Group A Streptococcus (GAS) causes superficial and invasive infections and immune
mediated post-infectious sequalae (including acute rheumatic fever/rheumatic heart …

Serological Profiling of Group A Streptococcus Infections in Acute Rheumatic Fever

N Lorenz, TKC Ho, R McGregor… - Clinical Infectious …, 2021 - academic.oup.com
Rheumatic fever is a serious post-infectious sequela of group A Streptococcus (GAS). Prior
GAS exposures were mapped in sera using a large panel of M-type specific peptides …

Immune Cross-Opsonization Withinemm Clusters Following Group AStreptococcus Skin Infection: Broadening the Scope of Type-Specific Immunity

HR Frost, D Laho, ML Sanderson-Smith… - Clinical infectious …, 2017 - academic.oup.com
Abstract Background Group A Streptococcus (GAS) skin infections are particularly prevalent
in developing nations. The GAS M protein, by which strains are differentiated into> 220 …

Acute rheumatic fever after group A Streptococcus pyoderma and group G Streptococcus pharyngitis

L O'Sullivan, NJ Moreland, RH Webb… - The Pediatric …, 2017 - journals.lww.com
A case of acute rheumatic fever (ARF) in an Indigenous Maori child in New Zealand after
Group A Streptococcus pyoderma and Group G Streptococcus pharyngitis is reported. The …

Rheumatic heart disease in Indigenous young peoples

R Wyber, V Wade, A Anderson, Y Schreiber… - The Lancet Child & …, 2021 - thelancet.com
Indigenous children and young peoples live with an inequitable burden of acute rheumatic
fever and rheumatic heart disease. In this Review, we focus on the epidemiological burden …

Increased Breadth of Group A Streptococcus Antibody Responses in Children With Acute Rheumatic Fever Compared to Precursor Pharyngitis and Skin Infections

AL Whitcombe, R McGregor, J Bennett… - The Journal of …, 2022 - academic.oup.com
Abstract Background Group A Streptococcus (GAS) causes superficial pharyngitis and skin
infections as well as serious autoimmune sequelae such as acute rheumatic fever (ARF) …

Mapping autoantibodies in children with acute rheumatic fever

R McGregor, ML Tay, LH Carlton… - Frontiers in …, 2021 - frontiersin.org
Background Acute rheumatic fever (ARF) is a serious sequela of Group A Streptococcus
(GAS) infection associated with significant global mortality. Pathogenesis remains poorly …