Purpose Functional status and chronic health status are important baseline characteristics of
critically ill patients. The assessment of frailty on admission to the intensive care unit (ICU) …

Despite widespread influenza vaccination programs, influenza remains a major cause of
morbidity and mortality in older adults. Age-related changes in multiple aspects of the …

Importance The appropriate treatment target for systolic blood pressure (SBP) in older
patients with hypertension remains uncertain. Objective To evaluate the effects of intensive …

Background Some people with substantial Alzheimer's disease pathology at autopsy had
shown few characteristic clinical symptoms or signs of the disease, whereas others with little …

The two most commonly employed frailty measures are the frailty phenotype and the frailty
index. We compared them to examine whether they demonstrated common characteristics of …

Frailty is a clinical geriatric syndrome caused by physiological deficits across multiple
systems. These deficits make it challenging to sustain homeostasis required for the …

Aims The impact of frailty on outcomes in randomized heart failure with preserved ejection
fraction (HFpEF) trials has not been previously reported. This analysis sought to characterize …

Objectives (1) To examine how sedentary behaviour and moderate–vigorous (MVPA) are
each experienced during the day across different levels of frailty;(2) estimate and compare …

Background Frailty is a key determinant of clinical outcomes. We sought to describe frailty
among US Veterans and its association with mortality. Methods Nationwide retrospective …

There is increasing awareness of the detrimental health impact of frailty on older adults and
of the high prevalence of malnutrition in this segment of the population. Experts in these 2 …