Blood eosinophils and chronic obstructive pulmonary disease: a global initiative for chronic obstructive lung disease science committee 2022 review

D Singh, A Agusti, FJ Martinez, A Papi… - American journal of …, 2022 - atsjournals.org
The Global Initiative for Chronic Obstructive Lung Disease (GOLD) published its first report
for the diagnosis and management of chronic obstructive pulmonary disease (COPD) in …

Chronic obstructive pulmonary disease biomarkers and their interpretation

RA Stockley, DMG Halpin, BR Celli… - American journal of …, 2019 - atsjournals.org
The pathology and impact of chronic obstructive pulmonary disease (COPD) results from an
abnormal inflammatory process resulting in tissue damage with ineffective repair in …

Blood eosinophil count thresholds and exacerbations in patients with chronic obstructive pulmonary disease

JH Yun, A Lamb, R Chase, D Singh, MM Parker… - Journal of allergy and …, 2018 - Elsevier
Background Eosinophilic airway inflammation in patients with chronic obstructive pulmonary
disease (COPD) is associated with exacerbations and responsivity to steroids, suggesting …

Prevalence of persistent blood eosinophilia: relation to outcomes in patients with COPD

C Casanova, BR Celli, JP de-Torres… - European …, 2017 - Eur Respiratory Soc
The impact of blood eosinophilia in chronic obstructive pulmonary disease (COPD) remains
controversial. To evaluate the prevalence and stability of a high level of blood eosinophils …

Blood eosinophil counts and their variability and risk of exacerbations in COPD: a population-based study

M Miravitlles, M Monteagudo, I Solntseva… - Archivos de …, 2021 - Elsevier
Background There is controversy regarding the role of blood eosinophil levels as a
biomarker of exacerbation risk in chronic obstructive pulmonary disease (COPD). Our aim …

Blood eosinophils as biomarkers to drive treatment choices in asthma and COPD

K Kostikas, C Brindicci, F Patalano - Current drug targets, 2018 - ingentaconnect.com
Background: Asthma and COPD are complex, heterogeneous conditions comprising a wide
range of phenotypes, some of which are refractory to currently available treatments …

The normal distribution of the hypoxic ventilatory response and methodological impacts: A meta‐analysis and computational investigation

B Oeung, K Pham, IM Olfert, DJDL Zerda… - The Journal of …, 2023 - Wiley Online Library
The hypoxic ventilatory response (HVR) is the increase in breathing in response to reduced
arterial oxygen pressure. Over several decades, studies have revealed substantial …

Contemporary perspectives in COPD: patient burden, the role of gender and trajectories of multimorbidity

SC Buttery, M Zysman, SAA Vikjord… - …, 2021 - Wiley Online Library
An individual's experience of COPD is determined by many factors in addition to the
pathological features of chronic bronchitis and emphysema and the symptoms that derive …

Chronic obstructive pulmonary disease subpopulations and phenotyping

LN Segal, FJ Martinez - Journal of Allergy and Clinical Immunology, 2018 - Elsevier
Information for Category 1 CME Credit Credit can now be obtained, free for a limited time, by
reading the review articles in this issue. Please note the following instructions. Method of …

Role of type2 inflammatory biomarkers in chronic obstructive pulmonary disease

K Oishi, K Matsunaga, T Shirai, K Hirai… - Journal of Clinical …, 2020 - mdpi.com
Airway inflammation in chronic obstructive pulmonary disease (COPD) is typically thought to
be driven by Type1 immune responses, while Type2 inflammation appears to be present in …