An effective strategy for successful chemotherapy relies on creating compounds with high
selectivity against cancer cells compared to normal cells and relatively low cytotoxicity. One …

Heterocyclic compounds, especially those containing the pyrazole moiety, are highly
significant in organic chemistry and possess remarkable and diverse biological properties …

This review article provides a comprehensive overview of imidazole, triazine, and isatin
derivatives, focusing on their synthesis approaches and potential applications in …

Background: Synthesis of a series of 2-(dichloromethyl) pyrazolo [1, 5-a][1, 3, 5] triazines
was carried out and evaluated in vitro for their anticancer activity against a panel of 60 cell …

An approach to a series of new 5‐amino‐4‐cyanoxazoles is described. Synthesis of the title
compounds relied on a two‐step sequence including heterocyclization of 2‐amido‐3, 3 …

A number of sulfamides were obtained by reaction interaction of (5-(dichloromethylene)-2-
oxoimidazolidin-4-ylidene) sulfamoyl chloride with anilines, benzylamines, Boc-protected …

Experimental and theoretical study was employed to study the adsorption of the diuretic
drug, trichlormethiazide (TCM) molecule on AuNPs (TCMA). The stereoelectronic properties …

Abstract New pyrazolo [1, 5-a][1, 3, 5] triazines with a heteroaromatic substituent in position
4 and dichloromethyl moiety in position 2 were obtained via a heterocyclization reaction of …

In different conditions, from 3-acetyl-1H-isochromen-1-one three partial reduction products
were obtained, namely 3-(1-hydroxyethyl)-1H-isochromen-1-one, 3-(1-hydroxyethyl) …

A versatile and efficient protocol for the synthesis of library of N-(2, 4-diarylthiazol-5-yl)
benzamidines is described. We obtained a library of 25 diversity with different of substituents …