A potential therapeutic target in traditional Chinese medicine for ulcerative colitis: Macrophage polarization

Z Yang, S Lin, W Feng, Y Liu, Z Song, G Pan… - Frontiers in …, 2022 - frontiersin.org
Intestinal macrophages are the main participants of intestinal immune homeostasis and
intestinal inflammation. Under different environmental stimuli, intestinal macrophages can …

Dietary flavonoids–microbiota crosstalk in intestinal inflammation and carcinogenesis

L Wang, M Li, Y Gu, J Shi, J Yan, X Wang, B Li… - The Journal of …, 2024 - Elsevier
Colorectal cancer (CRC) is currently the third leading cancer and commonly develops from
chronic intestinal inflammation. A strong association was found between gut microbiota and …

Astragaloside Ⅳ alleviates ulcerative colitis by regulating the balance of Th17/Treg cells

Y Zhong, W Liu, Y Xiong, Y Li, Q Wan, W Zhou, H Zhao… - Phytomedicine, 2022 - Elsevier
Background Restoring immune homeostasis by targeting the Th17/Treg response is a
potentially valuable therapeutic strategy for ulcerative colitis (UC). Astragaloside IV (AS-Ⅳ) …

Macrophage polarization in inflammatory bowel disease

K Zhang, J Guo, W Yan, L Xu - Cell Communication and Signaling, 2023 - Springer
The growing prevalence of inflammatory bowel disease (IBD) has encouraged research
efforts, which have contributed to gradual improvements in our understanding of IBD …

Traditional Chinese medicine for the treatment of cancers of hepatobiliary system: from clinical evidence to drug discovery

J Wu, G Tang, CS Cheng, R Yeerken, YT Chan, Z Fu… - Molecular Cancer, 2024 - Springer
Hepatic, biliary, and pancreatic cancer pose significant challenges in the field of digestive
system diseases due to their highly malignant nature. Traditional Chinese medicine (TCM) …

Astragalus Mongholicus: A review of its anti-fibrosis properties

F Gong, R Qu, Y Li, Y Lv, J Dai - Frontiers in Pharmacology, 2022 - frontiersin.org
Background: Fibrosis-related diseases (FRD) include cerebral fibrosis, pulmonary fibrosis,
cardiac fibrosis, liver fibrosis, renal fibrosis, peritoneal fibrosis, etc. The effects of fibrosis can …

Traditional Chinese medicine and natural products: potential approaches for inflammatory bowel disease

S Yuan, Y Li, J Li, JC Xue, Q Wang, XT Hou… - Frontiers in …, 2022 - frontiersin.org
Inflammatory bowel disease (IBD) is a rare, recurrent, and intractable inflammation
obstruction of the stomach tract, usually accompanied by inflammation of cell proliferation …

Fermented Astragalus and its metabolites regulate inflammatory status and gut microbiota to repair intestinal barrier damage in dextran sulfate sodium-induced …

J Li, Y Ma, X Li, Y Wang, Z Huo, Y Lin, J Li… - Frontiers in …, 2022 - frontiersin.org
Fermentation represents an efficient biotechnological approach to increase the nutritional
and functional potential of traditional Chinese medicine. In this study, Lactobacillus …

Quercetin serves as the major component of Xiang-lian Pill to ameliorate ulcerative colitis via tipping the balance of STAT1/PPARγ and dictating the alternative …

H Zhou, C Yang, J Li, Y He, Y Huang, R Qin… - Journal of …, 2023 - Elsevier
Abstract Ethnopharmacological relevance The traditional Chinese herbal formula, Xiang-
lian Pill (XLP), is commonly prescribed for ulcerative colitis (UC) patients to relieve their …

Traditional Chinese medicine in regulating macrophage polarization in immune response of inflammatory diseases

S Chen, J Zeng, R Li, Y Zhang, Y Tao, Y Hou… - Journal of …, 2024 - Elsevier
Ethnopharmacological relevance Numerous studies have demonstrated that various
traditional Chinese medicines (TCMs) exhibit potent anti-inflammatory effects against …