Anticholinesterase toxicity and oxidative stress

D Milatovic, RC Gupta… - The Scientific World …, 2006 - Wiley Online Library
Anticholinesterase compounds, organophosphates (OPs) and carbamates (CMs) are
commonly used for a variety of purposes in agriculture and in human and veterinary …

Nitric oxide: a radical neurotransmitter in the central nervous system

SR Vincent - Progress in neurobiology, 1994 - Elsevier
The recent discovery of an enzyme which can synthesize the free radical gas nitric oxide
(NO) from L-arginine has shed new light on a number of curious, and, at first glance …

Physiological and pathophysiological roles of nitric oxide in the central nervous system

C Szabó - Brain research bulletin, 1996 - Elsevier
Nitric oxide (NO) is produced by three distinct isoforms of nitric oxide synthases in the central
nervous system. Here, the roles of nitric oxide in the central nervous system are reviewed …

[HTML][HTML] Anticonvulsant and proconvulsant roles of nitric oxide in experimental epilepsy models

EA Del-Bel, PR Oliveira, JAC Oliveira… - Brazilian Journal of …, 1997 - SciELO Brasil
The effect of acute (120 mg/kg) and chronic (25 mg/kg, twice a day, for 4 days) intraperitonial
injection of the nitric oxide (NO) synthase (NOS) inhibitor NG-nitro-L-arginine (L-NOARG) …

Paradoxical facilitation of pilocarpine-induced seizures in the mouse by MK-801 and the nitric oxide synthesis inhibitor L-NAME

MS Starr, BS Starr - Pharmacology Biochemistry and Behavior, 1993 - Elsevier
The sensitivity of pilocarpine-induced seizures to NMDA receptor blockade with MK-801, or
to inhibition of synthesis of the second messenger nitric oxide (NO) with N ω-nitro-L-arginine …

Inhibition of NO synthase increases the severity of kainic acid-induced seizures in rodents

LRP Penix, W Davis, S Subramaniam - Epilepsy research, 1994 - Elsevier
The nitric oxide (NO) synthase inhibitor N ω-nitro-l-arginine (NNA) and the putative brain-
selective NO synthase inhibitor 7-nitroindazole (7-NI) were used to determine the role of …

Biphasic modulation of GABA release by nitric oxide in the hippocampus of freely moving rats in vivo

SJ Getting, J Segieth, S Ahmad, CS Biggs, PS Whitton - Brain research, 1996 - Elsevier
The effect of altering hippocampal nitric oxide (NO) levels on basal and N-methyl-d-
aspartate receptor-evoked release of GABA has been studied in freely moving rats. N-Methyl …

Nitric oxide donors SIN-1 and SNAP promote nonrapid-eye-movement sleep in rats

L Kapas, JM Krueger - Brain research bulletin, 1996 - Elsevier
We previously showed that inhibition of brain NO production suppresses sleep in rats and
rabbits. In the present experiments we studied the effects of stimulation of NO-receptive …

Nitric oxide regulates excitatory amino acid release in a biphasic manner in freely moving rats

J Segieth, SJ Getting, CS Biggs, PS Whitton - Neuroscience letters, 1995 - Elsevier
The effect of altering hippocampal nitric oxide levels on basal and N-methyl-d-aspartate
(NMDA) receptor-evoked release of glutamate and aspartate has been studied in freely …

Organophosphate-induced brain injuries: delayed apoptosis mediated by nitric oxide

YB Kim, GH Hur, S Shin, DE Sok, JK Kang… - Environmental toxicology …, 1999 - Elsevier
The features of organophosphate-induced brain injuries were investigated. Rats were
poisoned intraperitoneally with 9 mg/kg (1.8 LD50) of diisopropylfluorophosphate …