Spinal cord repair: advances in biology and technology

G Courtine, MV Sofroniew - Nature medicine, 2019 - nature.com
Individuals with spinal cord injury (SCI) can face decades with permanent disabilities.
Advances in clinical management have decreased morbidity and improved outcomes, but …

Epidural spinal cord stimulation as an intervention for motor recovery after motor complete spinal cord injury

JT Hachmann, A Yousak, JJ Wallner… - Journal of …, 2021 - journals.physiology.org
Spinal cord injury (SCI) commonly results in permanent loss of motor, sensory, and
autonomic function. Recent clinical studies have shown that epidural spinal cord stimulation …

Mechanisms of stem cell therapy in spinal cord injuries

M Shinozaki, N Nagoshi, M Nakamura, H Okano - Cells, 2021 - mdpi.com
Every year, 0.93 million people worldwide suffer from spinal cord injury (SCI) with
irretrievable sequelae. Rehabilitation, currently the only available treatment, does not …

[HTML][HTML] Breathing control, brain, and bodily self-consciousness: toward immersive digiceuticals to alleviate respiratory suffering

S Betka, D Adler, T Similowski, O Blanke - Biological psychology, 2022 - Elsevier
Breathing is peculiar among autonomic functions through several characteristics. It
generates a very rich afferent traffic from an array of structures belonging to the respiratory …

Epidural electrical stimulation: a review of plasticity mechanisms that are hypothesized to underlie enhanced recovery from spinal cord injury with stimulation

JT Eisdorfer, RD Smit, KM Keefe, MA Lemay… - Frontiers in Molecular …, 2020 - frontiersin.org
Spinal cord injury (SCI) often results in life-long sensorimotor impairment. Spontaneous
recovery from SCI is limited, as supraspinal fibers cannot spontaneously regenerate to form …

[HTML][HTML] Stem cell-derived neuronal relay strategies and functional electrical stimulation for treatment of spinal cord injury

BQ Lai, X Zeng, WT Han, MT Che, Y Ding, G Li… - Biomaterials, 2021 - Elsevier
The inability of adult mammals to recover function lost after severe spinal cord injury (SCI)
has been known for millennia and is mainly attributed to a failure of brain-derived nerve fiber …

Emergence of epidural electrical stimulation to facilitate sensorimotor network functionality after spinal cord injury

JS Calvert, PJ Grahn, KD Zhao, KH Lee - Neuromodulation: Technology at …, 2019 - Elsevier
Background Traumatic spinal cord injury (SCI) disrupts signaling pathways between the
brain and spinal networks below the level of injury. In cases of severe SCI, permanent loss …

Electrophysiological guidance of epidural electrode array implantation over the human lumbosacral spinal cord to enable motor function after chronic paralysis

JS Calvert, PJ Grahn, JA Strommen, IA Lavrov… - Journal of …, 2019 - liebertpub.com
Epidural electrical stimulation (EES) of the spinal cord has been shown to restore function
after spinal cord injury (SCI). Characterization of EES-evoked motor responses has provided …

Potential of electric stimulation for the management of COVID-19

P Allawadhi, A Khurana, S Allwadhi, US Navik… - Medical hypotheses, 2020 - Elsevier
The COVID-19 pandemic is the most devastating health emergency that humans have seen
over the past century. The war against the disease has been handicapped by unavailability …

Transcutaneous Spinal Cord Stimulation Improves Respiratory Muscle Strength and Function in Subjects with Cervical Spinal Cord Injury

H Kumru, L García-Alén, A Ros-Alsina, S Albu… - Biomedicines, 2023 - mdpi.com
(1) Background: Respiratory muscle weakness is common following cervical spinal cord
injury (cSCI). Transcutaneous spinal cord stimulation (tSCS) promotes the motor recovery of …