Trends in prevalence of type 1 and type 2 diabetes in children and adolescents in the US, 2001-2017
Importance Changes in the prevalence of youth-onset diabetes have previously been
observed. Objective To estimate changes in prevalence of type 1 and type 2 diabetes in …
observed. Objective To estimate changes in prevalence of type 1 and type 2 diabetes in …
Fatty acid-mediated signaling as a target for developing type 1 diabetes therapies
I Díaz Ludovico, S Sarkar, E Elliott… - Expert Opinion on …, 2023 - Taylor & Francis
ABSTRACT Introduction Type 1 diabetes (T1D) is an autoimmune disease in which pro-
inflammatory and cytotoxic signaling drive the death of the insulin-producing β cells. This …
inflammatory and cytotoxic signaling drive the death of the insulin-producing β cells. This …
Technological readiness and implementation of genomic‐driven precision medicine for complex diseases
The fields of human genetics and genomics have generated considerable knowledge about
the mechanistic basis of many diseases. Genomic approaches to diagnosis, prognostication …
the mechanistic basis of many diseases. Genomic approaches to diagnosis, prognostication …
[HTML][HTML] Plasma protein biomarkers predict the development of persistent autoantibodies and type 1 diabetes 6 months prior to the onset of autoimmunity
ES Nakayasu, LM Bramer, C Ansong… - Cell Reports …, 2023 - cell.com
Summary Type 1 diabetes (T1D) results from autoimmune destruction of β cells. Insufficient
availability of biomarkers represents a significant gap in understanding the disease cause …
availability of biomarkers represents a significant gap in understanding the disease cause …
[HTML][HTML] The Reporting Quality of Machine Learning Studies on Pediatric Diabetes Mellitus: Systematic Review
Background Diabetes mellitus (DM) is a major health concern among children with the
widespread adoption of advanced technologies. However, concerns are growing about the …
widespread adoption of advanced technologies. However, concerns are growing about the …
Systematic review of type 1 diabetes biomarkers reveals regulation in circulating proteins related to complement, lipid metabolism, and immune response
S Sarkar, EC Elliott, HR Henry, ID Ludovico… - Clinical Proteomics, 2023 - Springer
Abstract Background Type 1 diabetes (T1D) results from an autoimmune attack of the
pancreatic β cells that progresses to dysglycemia and symptomatic hyperglycemia. Current …
pancreatic β cells that progresses to dysglycemia and symptomatic hyperglycemia. Current …
Integration of infant metabolite, genetic, and islet autoimmunity signatures to predict type 1 diabetes by age 6 years
BJM Webb-Robertson, ES Nakayasu… - The Journal of …, 2022 - academic.oup.com
Context Biomarkers that can accurately predict risk of type 1 diabetes (T1D) in genetically
predisposed children can facilitate interventions to delay or prevent the disease. Objective …
predisposed children can facilitate interventions to delay or prevent the disease. Objective …
Environmental exposures in machine learning and data mining approaches to diabetes etiology: A scoping review
Background Environmental exposures are implicated in diabetes etiology, but are poorly
understood due to disease heterogeneity, complexity of exposures, and analytical …
understood due to disease heterogeneity, complexity of exposures, and analytical …
Incomplete time-series gene expression in integrative study for islet autoimmunity prediction
Abstract Type 1 diabetes (T1D) outcome prediction plays a vital role in identifying novel risk
factors, ensuring early patient care and designing cohort studies. TEDDY is a longitudinal …
factors, ensuring early patient care and designing cohort studies. TEDDY is a longitudinal …
Lipidomics in diabetes
EJ Kim, R Ramachandran… - Current Opinion in …, 2022 - journals.lww.com
Lipidomics in diabetes : Current Opinion in Endocrinology, Diabetes and Obesity
Lipidomics in diabetes : Current Opinion in Endocrinology, Diabetes and Obesity Log in or …
Lipidomics in diabetes : Current Opinion in Endocrinology, Diabetes and Obesity Log in or …