Ecotoxicity of o-Chlorobenzylidene Malononitrile (CBM) and Toxicological Risk Assessment for SCLP Biological Cultures (Saccharomyces sp., Chlorella sp., Lactobacillus sp …

V Gheorghe, CG Gheorghe, A Bondarev, R Somoghi - Toxics, 2023 - mdpi.com
Toxic substances used as chemical weapons present a number of particularities that affect
the surrounding environment, having a wide range of action by disrupting the ecological …

Growth of Acinetobacter baumannii impacted by iron chelation

BM Eales, B Bai, PR Merlau… - Letters in Applied …, 2023 - academic.oup.com
Acinetobacter baumannii (AB) has become multidrug-resistant (MDR) in recent years, and,
currently, there are limited effective treatment options. Nutrient metals (eg iron) are essential …

Antibacterial and Antibiofilm Activities of Kaffir Lime Essential Oils and Their Active Constituents Against Staphylococcus aureus focusing on Sortase A

C Pontanayodsakorn, C Eurtivong, P Jiamboonsri - Heliyon, 2025 - cell.com
Staphylococcus aureus biofilm has become a global medical concern due to rising antibiotic
resistance. This study aimed to evaluate the potential activities of kaffir lime essential oils …

Rapid design of combination antimicrobial therapy against Acinetobacter baumannii

BM Eales, J Smith, N Pouya, CS Hudson… - Computers & chemical …, 2025 - Elsevier
Abstract Treatment of serious bacterial infections with antimicrobial agents, such as
antibiotics, is a major clinical challenge, because of growing bacterial resistance to multiple …

Rapid In Vitro Assessment of Antimicrobial Drug Effect Bridging Clinically Relevant Pharmacokinetics: A Comprehensive Methodology

M Nikolaou, VH Tam - Pharmaceutics, 2023 - mdpi.com
Rapid in vitro assessment of antimicrobial drug efficacy under clinically relevant
pharmacokinetic conditions is an essential element of both drug development and clinical …

Optimizing antimicrobial treatment schedules: some fundamental analytical results

G Katriel - Bulletin of Mathematical Biology, 2024 - Springer
This work studies fundamental questions regarding the optimal design of antimicrobial
treatment protocols, using pharmacodynamic and pharmacokinetic mathematical models …

Novel Therapy for Acinetobacter baumannii Infections

BM Eales - 2023 - uh-ir.tdl.org
Antimicrobial resistance (AMR) is an ever-present problem due to the evolving mechanisms
that bacteria use to evade antibiotics. According to the Centers for Disease Control Antibiotic …

Deciphering longitudinal optical-density measurements to guide clinical dosing regimen design: A model-based approach

I Kesisoglou, BM Eales, PR Merlau, VH Tam… - Computer methods and …, 2022 - Elsevier
Background Model-based analysis of longitudinal optical density measurements from a
bacterial suspension exposed to antibiotics has been proposed as a potentially efficient and …

Specificity of Solvatochromic Trehalose Probes for Mycobacteria Detection

SS Kumar - 2024 - escholarship.org
Tuberculosis (TB) remains as the second leading infectious killer worldwide. In 2022 alone,
1.3 million people died from TB, with the disease being most prevalent in low-resource …