A variety of evolutionary processes has led to the development of different organs to ensure
that internal fertilization occur successfully. Fallopian tubes are a particularly interesting …

Zona pellucida (ZP) is a glycoproteinaceous translucent matrix that surrounds the
mammalian oocyte and plays a critical role in the accomplishment of fertilization. In humans …

The number of children born since the origin of Assisted Reproductive Technologies (ART)
exceeds 5 million. The majority seem healthy, but a higher frequency of defects has been …

Mammalian oocytes are surrounded by an extracellular coat called the zona pellucida (ZP),
which, from an evolutionary point of view, is the most ancient of the coats that envelope …

Intra-embryo genome editing by CRISPR/Cas9 enables easy generation of gene-modified
animals by non-homologous end joining (NHEJ)-mediated frameshift mutations or homology …

A block to polyspermy is required for successful fertilisation and embryo survival in
mammals. A higher incidence of polyspermy is observed during in vitro fertilisation (IVF) …

In mammals including humans, failure in blastocyst hatching and implantation leads to early
embryonic loss and infertility. Prior to implantation, the blastocyst must hatch out of its …

This chapter intends to summarise the importance of sperm-and oocyte-derived factors in
the processes of sperm–oocyte binding and oocyte activation. First, we describe the initial …

During mammalian fertilisation, the zona pellucida (ZP) matrix surrounding the oocyte is
responsible for the binding of the spermatozoa to the oocyte and induction of the acrosome …

The management of free-roaming horses (Equus ferus) and burros (E. asinus) in the United
States has been referred to as a “wicked problem” because, although there are population …