Molecular pathology of endometrial carcinoma

X Matias‐Guiu, J Prat - Histopathology, 2013 - Wiley Online Library
This review paper discusses the main molecular alterations of endometrial carcinoma, the
most common cancer of the female genital tract. Two clinicopathological variants are …

Endometrial carcinoma: molecular alterations involved in tumor development and progression

A Yeramian, G Moreno-Bueno, X Dolcet, L Catasus… - Oncogene, 2013 - nature.com
In the western world, endometrial carcinoma (EC) is the most common cancer of the female
genital tract. The annual incidence has been estimated at 10–20 per 100 000 women. Two …

CD163, a novel therapeutic target, regulates the proliferation and stemness of glioma cells via casein kinase 2

T Chen, J Chen, Y Zhu, Y Li, Y Wang, H Chen, J Wang… - Oncogene, 2019 - nature.com
Glioma is a devastating cancer with a dismal prognosis and there is an urgent need to
discover novel glioma-specific antigens for glioma therapy. Previous studies have identified …

Posttranslational regulation of phosphatase and tensin homolog (PTEN) and its functional impact on cancer behaviors

W Xu, Z Yang, SF Zhou, N Lu - Drug design, development and …, 2014 - Taylor & Francis
The incidence of cancer is increasing worldwide, but the biochemical mechanisms for the
occurrence of cancer is not fully understood, and there is no cure for advanced tumors …

[HTML][HTML] Dopamine, by acting through its D2 receptor, inhibits insulin-like growth factor-I (IGF-I)-induced gastric cancer cell proliferation via up-regulation of Krüppel …

S Ganguly, B Basu, S Shome, T Jadhav, S Roy… - The American journal of …, 2010 - Elsevier
The overexpression of insulin-like growth factor receptor-I (IGF-IR) and the activation of its
signaling pathways both play critical roles in the development and progression of gastric …

Protein kinase 2 (CK2): A potential regulator of immune cell development and function in cancer

K Husain, TT Williamson, N Nelson… - Immunological …, 2021 - Taylor & Francis
Protein kinase CK2, formally known as casein kinase II, is ubiquitously expressed and highly
conserved serine/threonine or tyrosine kinase enzyme that regulates diverse signaling …

Protein kinase CK2α subunit over-expression correlates with metastatic risk in breast carcinomas: quantitative immunohistochemistry in tissue microarrays

S Giusiano, C Cochet, O Filhol… - European journal of …, 2011 - Elsevier
BACKGROUND: CK2α is a signalling molecule that participates in major events in solid
tumour progression. The aim of this study was to evaluate the prognostic significance of the …

[HTML][HTML] A novel three-dimensional culture system of polarized epithelial cells to study endometrial carcinogenesis

N Eritja, D Llobet, M Domingo, M Santacana… - The American journal of …, 2010 - Elsevier
Development of three-dimensional (3D) cultures that mimic in vivo tissue organization has a
pivotal role in the investigation of the involvement of cell adhesion and polarity genes in the …

Endometrioid carcinoma of the endometrium: pathologic and molecular features

A Azueta, S Gatius, X Matias-Guiu - Seminars in diagnostic pathology, 2010 - Elsevier
Endometrioid carcinoma of the endometrium is the most common type of endometrial
carcinoma. The microscopic appearance of the tumor resembles that of the proliferative …

SNP screening of central MHC-identified HLA-DMB as a candidate susceptibility gene for HIV-related Kaposi's sarcoma

B Aissani, AK Boehme, HW Wiener, S Shrestha… - Genes & …, 2014 - nature.com
The major histocompatibility complex (MHC) region on chromosome 6p21. 3 is suspected to
host susceptibility loci for HIV-related Kaposi's sarcoma (HIV-KS). A nested case–control …