Piano stool Ru (II)-arene complexes having three monodentate legs: A comprehensive review on their development as anticancer therapeutics over the past decade

S Swaminathan, J Haribabu, N Balakrishnan… - Coordination chemistry …, 2022 - Elsevier
The popularity of RAPTA-C in in vivo studies has steered the way for complexes of the type
[Ru (η 6-arene)(X)(Y)(Z)] n+ (where X, Y and Z are monodentate ligands) to be developed …

Design concepts of half-sandwich organoruthenium anticancer agents based on bidentate bioactive ligands

WDJ Tremlett, DM Goodman, TR Steel, S Kumar… - Coordination chemistry …, 2021 - Elsevier
The small molecule anticancer agent cisplatin and its Pt (II) analogs carboplatin and
oxaliplatin are widely used to treat a variety of tumorigenic diseases. Despite their structural …

Perspectives of medicinally privileged chalcone based metal coordination compounds for biomedical applications

DK Mahapatra, SK Bharti, V Asati, SK Singh - European journal of …, 2019 - Elsevier
Recent clinical reports have highlighted the increasing occurrence of drug resistance of
known therapeutics. Particularly, antibiotic resistant microorganisms and multidrug …

Recent advances in anticancer ruthenium Schiff base complexes

S Parveen - Applied Organometallic Chemistry, 2020 - Wiley Online Library
Nowadays in cancer treatment, both metal complexes and organic molecules are being
widely used. Current years have seen a surge of interest in the application of organometallic …

[HTML][HTML] Recent advances in biological and medicinal profile of schiff bases and their metal complexes: An updated version (2018–2023)

S Thakur, A Jaryal, A Bhalla - Results in Chemistry, 2024 - Elsevier
Schiff bases are most the widely used class of molecules in organic as well as in inorganic
chemistry and are well known for fabricating stable metal complexes. Schiff bases and their …

Mechanistic studies of arene–ruthenium (II) complexes with carbothioamidopyrazoles as alternative cancer drugs

P Hikisz, E Namiecińska, P Paneth, E Budzisz - Molecules, 2023 - mdpi.com
Arene–ruthenium (II) complexes with carbothioamidopyrazoles at the C-2 and C-5 positions
have been recognized as chemotherapeutic agent alternatives to cisplatin and its oxaliplatin …

Aminopyrimidines: Recent synthetic procedures and anticancer activities

E Venturini Filho, EMC Pinheiro, S Pinheiro, SJ Greco - Tetrahedron, 2021 - Elsevier
The pyrimidine scaffold represents one of the privileged structures in chemistry, and there
has been an increase in number of studies utilizing this scaffold and its derivatives. The …

Dimetallic Ru (II) arene complexes appended on bis-salicylaldimine induce cancer cell death and suppress invasion via p53-dependent signaling

FU Rahman, MZ Bhatti, A Ali, HQ Duong… - European Journal of …, 2018 - Elsevier
A series of bis-salicylaldimine ligands bearing two ON-donor functions were reacted with
dichloro (p-cymene) ruthenium (II) dimer in the presence of base (NaOAc) and a series of …

Ionic mononuclear [Fe] and heterodinuclear [Fe, Ru] bis (diphenylphosphino) alkane complexes: Synthesis, spectroscopy, DFT structures, cytotoxicity, and …

M Odachowski, R Neven, G Perversi, D Romano… - Journal of Inorganic …, 2023 - Elsevier
Abstract Iron (II) and Ru (II) half-sandwich compounds encompass some promising pre-
clinical anticancer agents whose efficacy may be tuned by structural modification of the …

Ru, Rh and Ir metal complexes of pyridyl chalcone derivatives: Their potent antibacterial activity, comparable cytotoxicity potency and selectivity to cisplatin

L Dkhar, V Banothu, E Pinder, RM Phillips, W Kaminsky… - Polyhedron, 2020 - Elsevier
Half sandwich ruthenium, rhodium and iridium complexes containing pyridyl chalcone
analogues (L1 and L2) are prepared by the reaction of [(arene) M (µ-Cl) Cl] 2 (arene …