Skeletal muscles are essential for vital functions such as movement, postural support,
breathing, and thermogenesis. Muscle tissue is largely composed of long, postmitotic …

Skeletal muscle is a malleable tissue capable of altering the type and amount of protein in
response to disruptions to cellular homeostasis. The process of exerciseinduced adaptation …

Adult skeletal muscle can regenerate in response to muscle damage. This ability is
conferred by the presence of myogenic stem cells called satellite cells. In response to stimuli …

During aging there is an increasing imbalance of energy intake and expenditure resulting in
obesity, frailty, and metabolic disorders. For decades, research has shown that caloric …

The development and maintenance of skeletal muscle and bone mass is critical for
movement, health and issues associated with the quality of life. Skeletal muscle and bone …

Mammalian target of rapamycin (mTOR) has emerged as a key regulator of skeletal muscle
development by governing distinct stages of myogenesis, but the molecular pathways …

Introduction Recent studies have revealed that rapamycin activates autophagy in human
chondrocytes preventing the development of osteoarthritis (OA) like changes in vitro, while …

Skeletal muscle plays a fundamental role in mobility, disease prevention, and quality of life.
Skeletal muscle mass is, in part, determined by the rates of protein synthesis, and …

Myogenesis is a complex and tightly regulated process, the end result of which is the
formation of a multinucleated myofibre with contractile capability. Typically, this process is …

Maternal obesity and over‐nutrition give rise to both obstetric problems and neonatal
morbidity. The objective of this study was to evaluate effects of maternal obesity and over …