Synovial inflammation in osteoarthritis progression

E Sanchez-Lopez, R Coras, A Torres… - Nature Reviews …, 2022 - nature.com
Osteoarthritis (OA) is a progressive degenerative disease resulting in joint deterioration.
Synovial inflammation is present in the OA joint and has been associated with radiographic …

High-fat, western-style diet, systemic inflammation, and gut microbiota: a narrative review

IJ Malesza, M Malesza, J Walkowiak, N Mussin… - Cells, 2021 - mdpi.com
The gut microbiota is responsible for recovering energy from food, providing hosts with
vitamins, and providing a barrier function against exogenous pathogens. In addition, it is …

The potential role of gut microbiota in Alzheimer's disease: from diagnosis to treatment

A Varesi, E Pierella, M Romeo, GB Piccini, C Alfano… - Nutrients, 2022 - mdpi.com
Gut microbiota is emerging as a key regulator of many disease conditions and its
dysregulation is implicated in the pathogenesis of several gastrointestinal and extraintestinal …

Interaction between lipopolysaccharide and gut microbiota in inflammatory bowel diseases

M Candelli, L Franza, G Pignataro, V Ojetti… - International journal of …, 2021 - mdpi.com
Lipopolysaccharides (LPSs) are bacterial surface glycolipids, produced by Gram-negative
bacteria. LPS is known to determine acute inflammatory reactions, particularly in the context …

[HTML][HTML] Prebiotic effect of dietary polyphenols: A systematic review

AM Alves-Santos, CSA Sugizaki, GC Lima… - Journal of Functional …, 2020 - Elsevier
Prebiotics are substrates selectively metabolized by hindgut microorganisms conferring
health benefits. Recent studies suggest polyphenols as candidate to prebiotics. Thus, this …

Melatonin mitigates aflatoxin B1‐induced liver injury via modulation of gut microbiota/intestinal FXR/liver TLR4 signaling axis in mice

S Liu, W Kang, X Mao, L Ge, H Du, J Li… - Journal of pineal …, 2022 - Wiley Online Library
Abstract Aflatoxin B1 (AFB1) is a widespread contaminant in foods and feedstuffs, and its
target organ is the liver. Melatonin (MT) has been shown to alleviate inflammation in organs …

Mycotoxin and gut microbiota interactions

P Guerre - Toxins, 2020 - mdpi.com
The interactions between mycotoxins and gut microbiota were discovered early in animals
and explained part of the differences in susceptibility to mycotoxins among species. Isolation …

Alterations in circulating fatty acid are associated with gut microbiota dysbiosis and inflammation in multiple sclerosis

M Saresella, I Marventano, M Barone… - Frontiers in …, 2020 - frontiersin.org
Background: Butyric acid (BA) is a short-chain fatty acid (SCFA) with anti-inflammatory
properties, which promotes intestinal barrier function. Medium-chain fatty acids (MCFA) …

Gut microbiota remodeling: A promising therapeutic strategy to confront hyperuricemia and gout

Z Wang, Y Li, W Liao, J Huang, Y Liu, Z Li… - Frontiers in cellular and …, 2022 - frontiersin.org
The incidence of hyperuricemia (HUA) and gout continuously increases and has become a
major public health problem. The gut microbiota, which colonizes the human intestine, has a …

The postprandial actions of GLP-1 receptor agonists: the missing link for cardiovascular and kidney protection in type 2 diabetes

MC Thomas, MT Coughlan, ME Cooper - Cell Metabolism, 2023 - cell.com
Recent clinical trials in people with type 2 diabetes have demonstrated beneficial actions on
heart and kidney outcomes following treatment with GLP-1RAs. In part, these actions are …