Both the discovery of biomarkers of schizophrenia and the verification of biological
hypotheses of schizophrenia are an essential part of the process of understanding the …

Background Individuals affected with autism often suffer additional co-morbidities such as
intellectual disability. The genes contributing to autism cluster on a relatively limited number …

CTNNB1 is the gene that encodes β-catenin which acts as a key player in the Wnt signaling
pathway and regulates cellular homeostasis. Most CTNNB1-related studies have been …

Schizophrenia is regarded as a neurodevelopmental disorder with its course progressing
throughout life. However, the aetiology and development of schizophrenia are still under …

The human body is commonly exposed to bisphenol A (BPA), which is widely used in
consumer and industrial products. BPA is an endocrine-disrupting chemical that has …

Rodent self-grooming is an important complex behavior, and its deficits are translationally
relevant to a wide range of neuropsychiatric disorders. Here, we analyzed a comprehensive …

Our understanding of the environmental and genetic factors contributing to the wide
spectrum of neuropsychiatric disorders has significantly increased in recent years …

Autism spectrum disorder (ASD), schizophrenia, and bipolar disorder are genetically
complex and heterogeneous neurodevelopmental disorders (NDDs) resulting from genetic …

Highlights•Inheritance of parental histones maintain the epigenome.•Separate pathways
transfer H2A-H2B and H3-H4 to DNA daughter strands.•Mixing old and new histones …

DNA methyltransferases (DNMTs) are widely expressed in the brain, dictating the
transcriptional activity of genes through various epigenetic mechanisms. Functional …