Pathogenicity and virulence of Staphylococcus aureus

GYC Cheung, JS Bae, M Otto - Virulence, 2021 - Taylor & Francis
Staphylococcus aureus is one of the most frequent worldwide causes of morbidity and
mortality due to an infectious agent. This pathogen can cause a wide variety of diseases …

Staphylococcal biofilm development: structure, regulation, and treatment strategies

K Schilcher, AR Horswill - Microbiology and Molecular Biology …, 2020 - Am Soc Microbiol
In many natural and clinical settings, bacteria are associated with some type of biotic or
abiotic surface that enables them to form biofilms, a multicellular lifestyle with bacteria …

ImmunoPET: concept, design, and applications

W Wei, ZT Rosenkrans, J Liu, G Huang, QY Luo… - Chemical …, 2020 - ACS Publications
Immuno-positron emission tomography (immunoPET) is a paradigm-shifting molecular
imaging modality combining the superior targeting specificity of monoclonal antibody (mAb) …

[HTML][HTML] Sustainability in peptide chemistry: current synthesis and purification technologies and future challenges

L Ferrazzano, M Catani, A Cavazzini, G Martelli… - Green …, 2022 - pubs.rsc.org
Developing greener synthesis processes is an inescapable necessity to transform the
industrial landscape, mainly in the pharmaceutical sector, into a long-term, sustainable …

Predicting secretory proteins with SignalP

H Nielsen - Protein function prediction: methods and protocols, 2017 - Springer
SignalP is the currently most widely used program for prediction of signal peptides from
amino acid sequences. Proteins with signal peptides are targeted to the secretory pathway …

[HTML][HTML] Developing natural products as potential anti-biofilm agents

L Lu, W Hu, Z Tian, D Yuan, G Yi, Y Zhou, Q Cheng… - Chinese medicine, 2019 - Springer
Biofilm is a natural form of bacterial growth ubiquitously in environmental niches. The biofilm
formation results in increased resistance to negative environmental influences including …

Bacterial secretion systems: an overview

ER Green, J Mecsas - Virulence mechanisms of bacterial …, 2016 - Wiley Online Library
One essential prokaryotic cell function is the transport of proteins from the cytoplasm into
other compartments of the cell, the environment, and/or other bacteria or eukaryotic cells—a …

Staphylococcal biofilms

M Otto - Microbiology spectrum, 2018 - Am Soc Microbiol
Staphylococci, with the leading species Staphylococcus aureus and Staphylococcus
epidermidis, are the most frequent causes of infections on indwelling medical devices. The …

Staphylococcus aureus biofilm: a complex developmental organism

DE Moormeier, KW Bayles - Molecular microbiology, 2017 - Wiley Online Library
Chronic biofilm‐associated infections caused by Staphylococcus aureus often lead to
significant increases in morbidity and mortality, particularly when associated with indwelling …

[HTML][HTML] Discovering Anti-Cancer Drugs via Computational Methods

W Cui, A Aouidate, S Wang, Q Yu, Y Li… - Frontiers in …, 2020 - frontiersin.org
New drug discovery has been acknowledged as a complicated, expensive, time-consuming,
and challenging project. It has been estimated that around 12 years and 2.7 billion USD, on …