Regulated cell death mediated by dedicated molecular machines, known as programmed
cell death, plays important roles in health and disease. Apoptosis, necroptosis and …

Copper, an essential trace element that exists in oxidized and reduced forms, has pivotal
roles in a variety of biological processes, including redox chemistry, enzymatic reactions …

Necroptosis, a programmed cell death mechanism distinct from apoptosis, has garnered
attention for its role in various pathological conditions. While initially recognized for its …

Currently, the typical combination therapy of programmed death ligand‐1 (PD‐L1)
antibodies with radiotherapy (RT) still exhibits impaired immunogenic antitumor response in …

Ferroptosis, a novel form of cell death regulation, was identified in 2012. It is characterized
by unique features that differentiate it from other types of cell death, including necrosis …

It is generally recognized that tumor cells proliferate more rapidly than normal cells. Due to
such an abnormally rapid proliferation rate, cancer cells constantly encounter the limits of …

Within the field of medical science, there is a great deal of interest in investigating cell death
pathways in the hopes of discovering new drugs. Over the past two decades …

Nutritional status and pyroptosis are important for host defence against infections. However,
the molecular link that integrates nutrient sensing into pyroptosis during microbial infection is …

Opinion statement Metformin is a first-line drug in the clinical treatment of type 2 diabetes. Its
main molecular mechanism involves the activation of adenosine 5′-monophosphate …

There is increasing need to expand availability of donor liver grafts, including steatotic livers.
However, the current use of steatotic grafts in liver transplantation is less acceptable due to …