The last decade witnessed the great advances in the development of nanomedicines. As a
kind of attractive nanomedicine, carrier-free nanomedicines received extensive …

Covalent modification of therapeutic compounds is a clinically proven strategy to devise
prodrugs with enhanced treatment efficacies. This prodrug strategy relies on the modified …

Squalene (SQ) is a natural compound, a precursor of various hormones in animals and
sterols in plants. It is considered a molecule with pharmacological, cosmetic, and nutritional …

Lipid–drug conjugates (LDCs) are drug molecules that have been covalently modified with
lipids. The conjugation of lipids to drug molecules increases lipophilicity and also changes …

The targeted delivery of a drug should result in enhanced therapeutic efficacy with low to
minimal side effects. This is a widely accepted concept, but limited in application due to lack …

Squalene is a natural lipid belonging to the terpenoid family and a precursor of cholesterol
biosynthesis. It is synthesized in humans and also in a wide array of organisms and …

In this work, hollow mesoporous silica nanoparticles (HMSNs) with three pore sizes were
manufactured to control the drug release rate, and the biological roles of these HMSNs were …

Nanoscience is often referred to as “key”,“horizontal”, or “enabling”, since it can virtually
encompass all technological areas. 1r4 Bringing together different areas of science …

There are numerous anticancer agents based on a prodrug approach. However, no attempt
has been made to review the ample available literature with a specific focus on the altered …

We report a strategy to make use of poly (lactic-co-glycolic acid) nanoparticle (PLGA NPs)
for co-delivery of docetaxel (DTX) as a model anticancer drug together with vitamin E TPGS …