Sex hormones in the cardiovascular system

RL dos Santos, FB da Silva, RF Ribeiro Jr… - … molecular biology and …, 2014 - degruyter.com
Gender-associated differences in the development of cardiovascular diseases have been
described in humans and animals. These differences could explain the low incidence of …

The Effect of Cannabidiol on Ischemia/Reperfusion-Induced Ventricular Arrhythmias: The Role of Adenosine A1 Receptors

E Gonca, F Darıcı - Journal of cardiovascular pharmacology …, 2015 - journals.sagepub.com
Cannabidiol (CBD) is a nonpsychoactive phytocannabinoid with anti-inflammatory activity
mediated by enhancing adenosine signaling. As the adenosine A1 receptor activation …

Saving science through replication studies

JE Edlund, K Cuccolo, MS Irgens… - Perspectives on …, 2022 - journals.sagepub.com
The scientific enterprise has long been based on the presumption of replication, although
scientists have recently become aware of various corruptions of the enterprise that have hurt …

Estrogenic compounds, estrogen receptors and vascular cell signaling in the aging blood vessels

DA Smiley, RA Khalil - Current medicinal chemistry, 2009 - ingentaconnect.com
The cardiovascular benefits of menopausal hormone therapy (MHT) remain controversial.
The earlier clinical observations that cardiovascular disease (CVD) was less common in …

The beneficial effects of tamoxifen on arteries: a key player for cardiovascular health of breast cancer patient

M Davezac, C Meneur, M Buscato, R Zahreddine… - Biochemical …, 2023 - Elsevier
Breast cancer is the most common cancer in women. Over the past few decades, advances
in cancer detection and treatment have significantly improved survival rate of breast cancer …

Ginseng protects rodent hearts from acute myocardial ischemia–reperfusion injury through GR/ER-activated RISK pathway in an endothelial NOS-dependent …

H Zhou, SZ Hou, P Luo, B Zeng, JR Wang… - Journal of …, 2011 - Elsevier
Abstract Ethnopharmacological relevance Ginseng (Panax ginseng CA Meyer) is widely
used in Asian communities for treating cardiovascular diseases. However, the mechanism …

Thioredoxin-mediated redox regulation of resistance to endocrine therapy in breast cancer

RB Penney, D Roy - Biochimica et Biophysica Acta (BBA)-Reviews on …, 2013 - Elsevier
Resistance to endocrine therapy in breast carcinogenesis due to the redox regulation of the
signal transduction system by reactive oxygen species (ROS) is the subject of this review …

A Preliminary Evaluation of Advanced Oxidation Protein Products (AOPPs) as a Potential Approach to Evaluating Prognosis in Early-Stage Breast Cancer Patients and …

M Napiórkowska-Mastalerz, T Wybranowski, M Bosek… - Cancers, 2024 - mdpi.com
Simple Summary Breast cancer is the main cause of cancer-related deaths among women
globally. It clearly shows it is essential to find a useful marker, which could have a beneficial …

On the oxidative damage by cadmium to kidney mitochondrial functions

N Pavón, M Buelna-Chontal… - … and Cell Biology, 2019 - cdnsciencepub.com
In the kidney, the accumulation of heavy metals such as Cd2+ produces mitochondrial
dysfunctions, ie, uncoupling of the oxidative phosphorylation, inhibition of the electron …

Cardioprotective effects of long-term treatment with raloxifene, a selective estrogen receptor modulator, on myocardial ischemia/reperfusion injury in ovariectomized …

MT Chung, PY Cheng, KK Lam, SY Chen, YF Ting… - Menopause, 2010 - journals.lww.com
Objective: The aim of this study was to investigate the beneficial effect of long-term treatment
with raloxifene (RAL), a selective estrogen receptor modulator, on myocardial …