[HTML][HTML] Mycochemicals in wild and cultivated mushrooms: nutrition and health

F Cateni, ML Gargano, G Procida, G Venturella… - Phytochemistry …, 2022 - Springer
The mushrooms have contributed to the development of active ingredients of fundamental
importance in the field of pharmaceutical chemistry as well as of important tools in human …

A comprehensive review on phytochemical profiling in mushrooms: occurrence, biological activities, applications and future prospective

Y Zhou, M Chu, F Ahmadi, OT Agar… - Food Reviews …, 2024 - Taylor & Francis
Mushrooms have been an acclaimed food for their unique flavor and medicinal properties
since ancient times. Modern research shows that mushrooms are rich in various nutrients …

An updated review of bioactive peptides from mushrooms in a well-defined molecular weight range

N Landi, A Clemente, PV Pedone, S Ragucci… - Toxins, 2022 - mdpi.com
Here, we report the current status of the bioactive peptides isolated and characterized from
mushrooms during the last 20 years, considering 'peptide'a succession from to 2 to 100 …

Ageritin from pioppino mushroom: The prototype of ribotoxin-like proteins, a novel family of specific ribonucleases in edible mushrooms

S Ragucci, N Landi, R Russo, M Valletta, PV Pedone… - Toxins, 2021 - mdpi.com
Ageritin is a specific ribonuclease, extracted from the edible mushroom Cyclocybe aegerita
(synonym Agrocybe aegerita), which cleaves a single phosphodiester bond located within …

Characterization and cytotoxic activity of ribotoxin-like proteins from the edible mushroom Pleurotus eryngii

N Landi, M Grundner, S Ragucci, M Pavšič, M Mravinec… - Food Chemistry, 2022 - Elsevier
Ribotoxin-like proteins (RL-Ps) represent a novel specific ribonuclease family found in
edible mushrooms and are able to inhibit protein synthesis. Here, we report the …

Ribotoxic proteins, known as inhibitors of protein synthesis, from mushrooms and other fungi according to Endo's fragment detection

N Landi, HZF Hussain, PV Pedone, S Ragucci… - Toxins, 2022 - mdpi.com
rRNA N-glycosylases (EC 3.2. 2.22) remove a specific adenine (A4324, rat 28S rRNA) in the
sarcin ricin loop (SRL) involved into ribosome interaction with elongation factors, causing …

Ageritin, a Ribotoxin from Poplar Mushroom (Agrocybe aegerita) with Defensive and Antiproliferative Activities

L Citores, S Ragucci, JM Ferreras, A Di Maro… - ACS Chemical …, 2019 - ACS Publications
Ribotoxins make up a group of extracellular rRNA endoribonucleases produced by
ascomycetes that display cytotoxicity toward animal cells, having been proposed as …

[HTML][HTML] Quinoa as source of type 1 ribosome inactivating proteins: A novel knowledge for a revision of its consumption

N Landi, MR Ruocco, S Ragucci, F Aliotta, R Nasso… - Food Chemistry, 2021 - Elsevier
This study investigates on the presence of toxic proteins in quinoa seeds. To this aim, a
plethora of biochemical approaches were adopted for the purification and characterization of …

[HTML][HTML] Isolation, characterization and biological action of type-1 ribosome-inactivating proteins from tissues of Salsola soda L.

N Landi, S Ragucci, L Citores, A Clemente… - Toxins, 2022 - mdpi.com
Ribosome-inactivating proteins (RIPs) are known as RNA N-glycosylases. They depurinate
the major rRNA, damaging ribosomes and inhibiting protein synthesis. Here, new single …

Ribotoxin-like proteins from Boletus edulis: Structural properties, cytotoxicity and in vitro digestibility

N Landi, S Ragucci, R Culurciello, R Russo, M Valletta… - Food Chemistry, 2021 - Elsevier
Porcini are edible mushrooms widely used in cooking due to their extraordinary taste.
Despite this, cases of food poisoning have been reported in the recent literature also for …