Role of inflammatory cells in airway remodeling in COPD

Y Wang, J Xu, Y Meng, IM Adcock… - International journal of …, 2018 - Taylor & Francis
COPD is characterized by chronic bronchitis, chronic airway obstruction, and emphysema,
leading to a progressive and irreversible decline in lung function. Inflammation is central for …

[HTML][HTML] Air pollutants and early origins of respiratory diseases

D Kim, Z Chen, LF Zhou, SX Huang - Chronic diseases and translational …, 2018 - Elsevier
Air pollution is a global health threat and causes millions of human deaths annually. The late
onset of respiratory diseases in children and adults due to prenatal or perinatal exposure to …

Next-generation TB vaccines: progress, challenges, and prospects

L Zhuang, Z Ye, L Li, L Yang, W Gong - Vaccines, 2023 - mdpi.com
Tuberculosis (TB), caused by Mycobacterium tuberculosis (MTB), is a prevalent global
infectious disease and a leading cause of mortality worldwide. Currently, the only available …

Immunomodulatory actions of vitamin D in various immune-related disorders: a comprehensive review

A Ghaseminejad-Raeini, A Ghaderi, A Sharafi… - Frontiers in …, 2023 - frontiersin.org
For many years, vitamin D has been acknowledged for its role in maintaining calcium and
phosphate balance. However, in recent years, research has assessed its …

The role of lymphocytes in radiotherapy-induced adverse late effects in the lung

F Wirsdörfer, V Jendrossek - Frontiers in immunology, 2016 - frontiersin.org
Radiation-induced pneumonitis and fibrosis are dose-limiting side effects of thoracic
irradiation. Thoracic irradiation triggers acute and chronic environmental lung changes that …

Alarmins and innate lymphoid cells 2 activation: A common pathogenetic link connecting respiratory syncytial virus bronchiolitis and later wheezing/asthma?

GA Rossi, S Ballarini, P Salvati… - Pediatric Allergy and …, 2022 - Wiley Online Library
Severe respiratory syncytial virus (RSV) infection in infancy is associated with increased risk
of recurrent wheezing in childhood. Both acute and long‐term alterations in airway functions …

Plasma microRNA-21, microRNA-146a and IL-13 expression in asthmatic children

R Hammad Mahmoud Hammad… - Innate …, 2018 - journals.sagepub.com
Childhood asthma represents a worldwide problem, involving genetic, immune defense and
environmental components. MicroRNAs (miRs) are non-coding, single-stranded RNAs …

The origin and role of innate lymphoid cells in the lung

DM Lai, Q Shu, J Fan - Military Medical Research, 2016 - Springer
Innate lymphoid cells (ILCs), a newly identified member of the lymphoid population, play a
critical role in the transition from innate to adaptive immunity in host defense. ILCs are …

[HTML][HTML] Lipoxin A4 regulates PM2. 5-induced severe allergic asthma in mice via the Th1/Th2 balance of group 2 innate lymphoid cells

X Lu, H Fu, F Han, Y Fang, J Xu, L Zhang… - Journal of thoracic …, 2018 - ncbi.nlm.nih.gov
Background Urban particulate matter (PM) contributes to the increasing number of people
with asthma, which is closely related to the development of industrialization. Especially, PM …

Isolation and identification of innate lymphoid cells (ILCs) for immunotoxicity testing

ED Tait Wojno, CA Beamer - Immunotoxicity Testing: Methods and …, 2018 - Springer
Innate lymphoid cells (ILCs) comprise a family of innate immune cells that orchestrate
mucosal immune responses: initiating, sustaining, and even curbing immune responses …