CD4 cell count threshold for cryptococcal antigen screening of HIV-infected individuals: a systematic review and meta-analysis

N Ford, Z Shubber, JN Jarvis, T Chiller… - Clinical Infectious …, 2018 - academic.oup.com
Background Current guidelines recommend screening all people living with human
immunodeficiency virus (PLHIV) who have a CD4 count≤ 100 cells/µL for cryptococcal …

New insights into HIV/AIDS‐associated cryptococcosis

S Antinori - International Scholarly Research Notices, 2013 - Wiley Online Library
Cryptococcal meningitis is a life‐threatening opportunistic fungal infection in both HIV‐
infected and HIV‐uninfected patients. According to the most recent taxonomy, the …

Invasive fungal diseases in Africa: a critical literature review

F Bongomin, BE Ekeng, W Kibone, L Nsenga, R Olum… - Journal of Fungi, 2022 - mdpi.com
Invasive fungal diseases (IFDs) are of huge concern in resource-limited settings, particularly
in Africa, due to the unavailability of diagnostic armamentarium for IFDs, thus making …

Cryptococcal and Histoplasma Antigen Screening Among People With Human Immunodeficiency Virus in Ghana and Comparative Analysis of OIDx Histoplasma Lateral Flow …

BK Ocansey, B Otoo, I Asamoah, V Ganu… - Open Forum …, 2022 - academic.oup.com
Background Cryptococcal meningitis (CM) and disseminated histoplasmosis (DH) are
common in people with human immunodeficiency virus (PWH) and diagnosed by detecting …

Impact of routine cryptococcal antigen screening and targeted preemptive fluconazole therapy in antiretroviral-naive human immunodeficiency virus–infected adults …

E Temfack, JJ Bigna, HN Luma, R Spijker… - Clinical Infectious …, 2019 - academic.oup.com
Cryptococcal antigen (CrAg) screening and targeted preemptive fluconazole in antiretroviral-
naive human immunodeficiency virus–infected adults with CD4 cell counts< 100/μL seems …

Prevalence and mortality of cryptococcal disease in adults with advanced HIV in an urban tertiary hospital in Sierra Leone: a prospective study

S Lakoh, H Rickman, M Sesay, S Kenneh… - BMC infectious …, 2020 - Springer
Background The global annual estimate for cryptococcal disease-related deaths exceeds
180,000, with three fourth occurring in sub-Saharan Africa. The World Health Organization …

Comparison of cryptococcal antigenemia between antiretroviral naïve and antiretroviral experienced HIV positive patients at two hospitals in Ethiopia

T Beyene, Y Woldeamanuel, D Asrat, G Ayana… - PLoS …, 2013 - journals.plos.org
Background Cryptococcal meningitis is a major cause of HIV/AIDS-related deaths in Africa.
Cryptococcosis is a neglected killer. However, meningitis can be prevented by early …

Estimated burden of serious fungal infections in Ghana

BK Ocansey, GA Pesewu, FS Codjoe, S Osei-Djarbeng… - Journal of Fungi, 2019 - mdpi.com
Fungal infections are increasingly becoming common and yet often neglected in developing
countries. Information on the burden of these infections is important for improved patient …

Cryptococcal antigen screening and early antifungal treatment to prevent cryptococcal meningitis: a review of the literature

JE Kaplan, S Vallabhaneni, RM Smith… - JAIDS Journal of …, 2015 - journals.lww.com
Background: Screening individuals with AIDS for serum cryptococcal antigen (CrAg),
followed by treatment of CrAg positives with antifungals, may prevent cryptococcal …

Preventing cryptococcosis—shifting the paradigm in the era of highly active antiretroviral therapy

D Meya, R Rajasingham, E Nalintya… - … tropical medicine reports, 2015 - Springer
Cryptococcosis remains a significant cause of morbidity and mortality among HIV-infected
patients, especially in sub-Saharan Africa where it causes up to 20% of AIDS-related deaths …