Cobalt: its role in health and disease

K Yamada - Interrelations between essential metal ions and human …, 2013 - Springer
The primarily function of cobalt in humans is based on its role in cobalamin (Cbl, vitamin B
12). Therefore, this chapter will focus on the physiological roles of Cbl and the importance of …

Recent advances and promises in nitrile hydratase: from mechanism to industrial applications

Z Cheng, Y Xia, Z Zhou - Frontiers in bioengineering and …, 2020 - frontiersin.org
Nitrile hydratase (NHase, EC 4.2. 1.84) is one type of metalloenzyme participating in the
biotransformation of nitriles into amides. Given its catalytic specificity in amide production …

Biodegradation of the Neonicotinoid Insecticide Acetamiprid by Actinomycetes Streptomyces canus CGMCC 13662 and Characterization of the Novel Nitrile …

L Guo, WW Fang, LL Guo, CF Yao… - Journal of agricultural …, 2019 - ACS Publications
Neonicotinoid insecticide pollution in soil and water poses serious environmental risks.
Microbial biodegradation is an important neonicotinoid insecticide degradation pathway in …

Unicellular cyanobacteria degrade sulfoxaflor to its amide metabolite of potentially higher aquatic toxicity

P Łukaszewicz, P Siudak, K Kropidłowska, M Caban… - Chemosphere, 2023 - Elsevier
Sulfoxaflor (SFX) is a fourth-generation neonicotinoid used widely in modern agriculture.
Due to its high water solubility and mobility in environment, it is expected to occur in water …

Advances in cloning, structural and bioremediation aspects of nitrile hydratases

K Supreetha, SN Rao, D Srividya, HS Anil… - Molecular biology …, 2019 - Springer
Nitrile hydratase (NHase) is a prominent enzyme in many microorganisms for its nitrile
metabolism. The potentiality in the bioconversion of nitriles to its high-value amides has …

An archaeal nitrile hydratase from the halophilic archaeon A07HB70 exhibits high tolerance to 3-cyanopyridine and nicotinamide

J Guo, Z Cheng, Z Zhou - Protein Expression and Purification, 2024 - Elsevier
Abstract Nitrile hydratase (NHase, EC 4.2. 1.84) is widely used in the industrial production of
biosynthetic amide compounds. NHases obtained from prokaryotic and eukaryotic sources …

Diversity of nitrogen assimilation pathways among microbial photosynthetic eukaryotes

R Terrado, A Monier, R Edgar… - Journal of Phycology, 2015 - Wiley Online Library
In an effort to better understand the diversity of genes coding for nitrogen (N) uptake and
assimilation pathways among microalgae, we analyzed the transcriptomes of five …

Random mutagenesis of the arylacetonitrilase from Pseudomonas fluorescens EBC191 and identification of variants, which form increased amounts of …

O Sosedov, A Stolz - Applied microbiology and biotechnology, 2014 - Springer
The nitrilase from Pseudomonas fluorescens EBC191 was modified by introducing random
mutations via error-prone PCR techniques in order to obtain nitrilase variants, which form …

Development of high-performance nitrile hydratase whole-cell catalyst by automated structure-and sequence-based design and mechanism insights

M Li, D Ma, J Qiao, Z Cheng, Q Wang, Z Zhou… - Systems Microbiology …, 2024 - Springer
Nitrile hydratase (NHase) is a metalloenzyme that catalyzes the conversion of nitrile to
amide and is widely used in the biocatalysis of bulk chemicals such as acrylamide and …

[HTML][HTML] New cblA gene participates in regulation of cobalt-dependent transcription of nitrile hydratase genes in Rhodococcus rhodochrous

KV Lavrov, AO Shemyakina, EG Grechishnikova… - Research in …, 2018 - Elsevier
Rhodococcus strains are important biocatalysts used for biotechnological production of
acrylamide catalysed by a nitrile hydratase (NHase) containing cobalt. This metalloenzyme …