Parkinson's disease (PD), a neurodegenerative disorder characterized by distinct aging-
independent loss of dopaminergic neurons in substantia nigra pars compacta (SNpc) region …

Acetylcholinesterase (AChE) plays an important role in the pathogenesis of
neurodegenerative diseases by influencing the inflammatory response, apoptosis, oxidative …

Pathological aggregation of intrinsically disordered tau protein, driven by the interactions
between microtubule-binding (MTB) domains, is associated with Alzheimer's disease. The …

Amyloid depositions of human islet amyloid polypeptides (hIAPP) are associated with type II
diabetes (T2D) impacting millions of people globally. Accordingly, strategies against hIAPP …

The relationship between gut microbiota and neurodegenerative diseases is becoming
clearer. Among said diseases amyotrophic lateral sclerosis (ALS) stands out due to its …

Deposition of misfolded protein aggregates in key areas of human brain is the quintessential
trait of various pertinent neurodegenerative disorders including amyotrophic lateral sclerosis …

Mitochondria, fundamental cellular organelles that govern energy metabolism, hold a pivotal
role in cellular vitality. While consuming dioxygen to produce adenosine triphosphate (ATP) …

Amyotrophic lateral sclerosis (ALS) is a fatal illness characterized by progressive motor
neuron degeneration. Conventional therapies for ALS are based on treatment of symptoms …

Protein misfolding is a biological process that leads to protein aggregation. Anomalous
misfolding and aggregation of human superoxide dismutase (hSOD1) into amyloid …

Antimicrobial peptides (AMPs) are persisting in all living organisms as evolutionarily
conserved inherent components of the innate immune system. Due to relatively lower …