Interferon-induced transmembrane proteins (IFITMs) are broad spectrum antiviral factors that
inhibit the entry of a wide range of clinically important pathogens including influenza A virus …

Interferons (IFNs) are important cytokines that regulate immune responses through the
activation of hundreds of genes, including interferon-induced transmembrane proteins …

Interferon-induced transmembrane proteins (IFITMs 1, 2 and 3) can restrict viral pathogens,
but pro-and anti-viral activities have been reported for coronaviruses. Here, we show that …

Platelets and megakaryocytes are critical players in immune responses. Recent reports
suggest infection and inflammation alter the megakaryocyte and platelet transcriptome to …

Background Recent evidence has linked the interferon-induced transmembrane protein 3
gene (IFITM3) to coronavirus disease 2019 (COVID-19) outcomes, but the results are …

The search for cell-permeable drugs has conventionally focused on low-molecular weight
(MW), nonpolar, rigid chemical structures. However, emerging therapeutic strategies break …

Interferon gamma (IFNγ) is a critical cytokine known for its diverse roles in immune
regulation, inflammation, and tumor surveillance. However, while IFNγ levels were elevated …

Interferon-induced transmembrane proteins (IFITM1, 2, and 3) are important antiviral
proteins that are active against many viruses, including influenza A virus (IAV), dengue virus …

Interferon-induced transmembrane protein 3 (IFITM3) is an interferon-induced membrane
protein, which has been identified as a functional gene in multiple human cancers. The role …

Long noncoding RNAs (lncRNAs) are involved in numerous cellular processes. Increasing
evidence suggests that some lncRNAs function in immunity through various complex …