Tailoring multi-omics to inflammatory bowel diseases: all for one and one for all

P Sudhakar, D Alsoud, J Wellens… - Journal of Crohn's …, 2022 - academic.oup.com
Inflammatory bowel disease [IBD] has a multifactorial origin and originates from a complex
interplay of environmental factors with the innate immune system at the intestinal epithelial …

Cyber-attacks and threats for healthcare–a multi-layer thread analysis

EG Spanakis, S Bonomi, S Sfakianakis… - 2020 42nd Annual …, 2020 - ieeexplore.ieee.org
Due to the advent of novel technologies and digital opportunities allowing to simplify user
lives, healthcare is increasingly evolving towards digitalization. This represent a great …

[HTML][HTML] Navigating multi-scale cancer systems biology towards model-driven clinical oncology and its applications in personalized therapeutics

MN Gondal, SU Chaudhary - Frontiers in Oncology, 2021 - frontiersin.org
Rapid advancements in high-throughput omics technologies and experimental protocols
have led to the generation of vast amounts of scale-specific biomolecular data on cancer …

[HTML][HTML] Emerging and established trends to support secure Health Information Exchange

EG Spanakis, S Sfakianakis, S Bonomi… - Frontiers in Digital …, 2021 - frontiersin.org
This work aims to provide information, guidelines, established practices and standards, and
an extensive evaluation on new and promising technologies for the implementation of a …

[HTML][HTML] PharmActa: Personalized pharmaceutical care eHealth platform for patients and pharmacists

M Spanakis, S Sfakianakis, G Kallergis… - Journal of Biomedical …, 2019 - Elsevier
Community pharmacists are critically placed in the patient care chain being an extended
frontline within primary healthcare networks across Europe. They are trained to ensure safe …

Atlas-based segmentation of brain tumor images using a Markov random field-based tumor growth model and non-rigid registration

S Bauer, C Seiler, T Bardyn… - … conference of the …, 2010 - ieeexplore.ieee.org
We propose a new and clinically oriented approach to perform atlas-based segmentation of
brain tumor images. A mesh-free method is used to model tumor-induced soft tissue …

The ObTiMA system–ontology-based managing of clinical trials

H Stenzhorn, G Weiler, M Brochhausen… - MEDINFO …, 2010 - ebooks.iospress.nl
Abstract Clinical Trial Management Systems promise to help researchers in managing the
large amounts of data occurring in clinical trials. In such systems Case Report Forms for …

Segmentation of brain tumor images based on atlas-registration combined with a Markov-Random-Field lesion growth model

S Bauer, LP Nolte, M Reyes - 2011 IEEE International …, 2011 - ieeexplore.ieee.org
We present an automatic method to segment brain tissues from volumetric MRI brain tumor
images. The method is based on non-rigid registration of an average atlas in combination …

Clinically driven design of multi-scale cancer models: the ContraCancrum project paradigm

K Marias, D Dionysiou, V Sakkalis, N Graf… - Interface …, 2011 - royalsocietypublishing.org
The challenge of modelling cancer presents a major opportunity to improve our ability to
reduce mortality from malignant neoplasms, improve treatments and meet the demands …

[HTML][HTML] Diffusive modelling of glioma evolution: a review

A Roniotis, K Marias, V Sakkalis, M Zervakis - Journal of Biomedical …, 2010 - scirp.org
Gliomas, the most aggressive form of brain cancer, are known for their widespread invasion
into the tissue near the tumor lesion. Exponential models, which have been widely used in …