[HTML][HTML] Molecular Pathways and Potential Therapeutic Targets of Refractory Asthma

L Ishmael, T Casale, JC Cardet - Biology, 2024 - mdpi.com
Simple Summary Refractory asthma is a complex and heterogeneous disease. The
molecular pathways and cells involved in refractory asthma include T2 and non-T2 …

Severe allergy as a chronic inflammatory condition from a systems biology perspective

MI Delgado Dolset, C Pablo‐Torres… - Clinical & …, 2024 - Wiley Online Library
Persistent and unresolved inflammation is a common underlying factor observed in several
and seemingly unrelated human diseases, including cardiovascular and neurodegenerative …

Lipid species profiling of bronchoalveolar lavage fluid cells of horses housed on two different bedding materials

J Mönki, M Holopainen, H Ruhanen, N Karikoski… - Scientific reports, 2023 - nature.com
The lipidome of equine BALF cells has not been described. The objectives of this
prospective repeated-measures study were to explore the BALF cells' lipidome in horses …

Analytical challenges in omics research on asthma and allergy: A National Institute of Allergy and Infectious Diseases workshop

S Bunyavanich, PM Becker, MC Altman… - Journal of Allergy and …, 2024 - Elsevier
Studies of asthma and allergy are generating increasing volumes of omics data for analysis
and interpretation. The National Institute of Allergy and Infectious Diseases (NIAID) …

Unraveling heterogeneity and treatment of asthma through integrating multi-omics data

W Zhang, Y Zhang, L Li, R Chen, F Shi - Frontiers in Allergy, 2024 - frontiersin.org
Asthma has become one of the most serious chronic respiratory diseases threatening
people's lives worldwide. The pathogenesis of asthma is complex and driven by numerous …

Promising treatment biomarkers in asthma

B Bonnesen, JUS Jensen, AG Mathioudakis… - Frontiers in Drug …, 2023 - frontiersin.org
Asthma is a highly heterogenous disease which researchers over time have attempted to
classify into different phenotypes and endotypes to improve diagnosis, prognosis and …

Association between serum lipid and all-cause mortality in asthmatic populations: a cohort study

J Wen, R Zhuang, Q He, C Wei, M Giri, J Chi - Lipids in Health and …, 2024 - Springer
Background Presently, the majority of investigations primarily evaluate the association
between lipid profiles and asthma. However, few investigations explore the connection …

Glycerolipids disrupt regulatory T-cells in asthma

FB Oktelik, M Benamar - European Respiratory Journal, 2024 - publications.ersnet.org
Extract Asthma is a chronic inflammatory disease that arises due to an exacerbated immune
response causing narrowing and hypersensitivity of the airways [1]. The full aetiology of …

Role of Complement Components in Asthma: A Systematic Review

I Tornyi, I Horváth - Journal of Clinical Medicine, 2024 - mdpi.com
Background: Asthma is a chronic inflammatory airway disease characterized by recurrent
symptoms in response to a wide range of external stimuli, including allergens, viral …

Lower myostatin and higher MUC1 levels are associated with better response to mepolizumab and omalizumab in asthma: a protein–protein interaction analyses

A Akenroye, T Nopsopon, L Cho, M Moll… - Respiratory Research, 2023 - Springer
Introduction Biomarkers are needed to inform the choice of biologic therapy in patients with
asthma given the increasing number of biologics. We aimed to identify proteins associated …