1, 2, 3-Triazole-containing hybrids as leads in medicinal chemistry: A recent overview

K Bozorov, J Zhao, HA Aisa - Bioorganic & medicinal chemistry, 2019 - Elsevier
Abstract The 1, 2, 3-triazole ring is a major pharmacophore system among nitrogen-
containing heterocycles. These five-membered heterocyclic motifs with three nitrogen …

Versatile synthetic platform for 1, 2, 3-triazole chemistry

DP Vala, RM Vala, HM Patel - Acs Omega, 2022 - ACS Publications
1, 2, 3-Triazole scaffolds are not obtained in nature, but they are still intensely investigated
by synthetic chemists in various fields due to their excellent properties and green synthetic …

Thiophene-based derivatives as anticancer agents: An overview on decade's work

S Pathania, PA Chawla - Bioorganic Chemistry, 2020 - Elsevier
Heterocyclic compounds hold a pivotal place in medicinal chemistry due to their wide range
of biological activities and thus, are exhaustively explored in the field of drug design and …

2-Aminothiophene scaffolds: Diverse biological and pharmacological attributes in medicinal chemistry

K Bozorov, LF Nie, J Zhao, HA Aisa - European journal of medicinal …, 2017 - Elsevier
Aminothiophenes are important five-membered heterocyclic building blocks in organic
synthesis, and the chemistry of these small molecules is still developing based on the …

Endophytic Bacteria Associated with Medicinal Plant Vernonia anthelmintica: Diversity and Characterization

N Rustamova, A Wubulikasimu, N Mukhamedov… - Current …, 2020 - Springer
Increasing evidence shows that endophytic bacteria living inside plant tissue may possess
similar biological activity and produce similar metabolites to their hosts. This study aimed to …

Thiophene‐containing compounds with antimicrobial activity

G Roman - Archiv der Pharmazie, 2022 - Wiley Online Library
Thiophene, as a member of the group of five‐membered heterocycles containing one
heteroatom, is one of the simplest heterocyclic systems. Many synthetic strategies allow the …

Biological Activity of Endophytic Fungi from the Roots of the Medicinal Plant Vernonia anthelmintica

N Rustamova, Y Gao, Y Zhang, A Yili - Microorganisms, 2020 - mdpi.com
Endophytic fungi were first isolated from the fresh root of the Chinese medicinal plant
Vernonia anthelmintica collected from the Hotan Prefecture within the Xinjiang Autonomous …

Synthesis and evaluation of RNase L-binding 2-aminothiophenes as anticancer agents

J Hwang, X Qiu, L Borgelt, N Haacke, L Kanis… - Bioorganic & Medicinal …, 2022 - Elsevier
Aminothiophene is a scaffold that is widely present in drugs and biologically active small
molecules as chemical probes. In this study, 43 compounds sharing a 2-aminothiophenone …

Piperazine-Grafted Magnetic Reduced Graphene Oxide (Fe3O4@rGO-NH) as a Reusable Heterogeneous Catalyst for Gewald Three-Component Reaction

E Rezaei-Seresht, M Bakhshi-Noroozi… - Polycyclic Aromatic …, 2021 - Taylor & Francis
In recent years, interesting physical and chemical properties of graphene oxide (GO) have
led to a great deal of excitement in the chemistry. One of the most promising results is the …

Access to 2‐Amino‐3‐Arylthiophenes by Base‐Catalyzed Redox Condensation Reaction Between Arylacetonitriles, Chalcones, and Elemental Sulfur

TTT Nguyen, VA Le, P Retailleau… - Advanced Synthesis & …, 2020 - Wiley Online Library
A straightforward access to 2‐amino‐3‐arylthiophenes has been developed via one‐pot two‐
step three‐component reaction of arylacetonitriles, chalcones and elemental sulfur. The first …