Background According to recent evidence, up to 40–50% of variance in autism spectrum
disorder (ASD) liability might be determined by environmental factors. In the present paper …

Abstract The Endocrine Society's first Scientific Statement in 2009 provided a wake-up call to
the scientific community about how environmental endocrine-disrupting chemicals (EDCs) …

Wildlife has often presented and suggested the effects of endocrine disrupting chemicals
(EDCs). Animal studies have given us an important opportunity to understand the …

The metabolism of polychlorinated biphenyls (PCBs) is complex and has an impact on
toxicity, and thereby on the assessment of PCB risks. A large number of reactive and stable …

Persistent organic pollutants (POPs) are lipophilic compounds that travel with lipids and
accumulate mainly in adipose tissue. Recent human evidence links low-dose POPs to an …

An endocrine-disrupting chemical (EDC) is an exogenous chemical, or mixture of chemicals,
that can interfere with any aspect of hormone action. The potential for deleterious effects of …

Thyroid hormones are crucial in normal brain development. Transient and mild thyroid
hormone insufficiency in pregnancy is also associated with impaired neurodevelopment in …

Abstract The European Commission asked EFSA for a scientific opinion on the risks for
animal and human health related to the presence of dioxins (PCDD/Fs) and DL‐PCBs in …

Polychlorinated biphenyls (PCBs) are developmental neurotoxicants implicated as
environmental risk factors for neurodevelopmental disorders (NDDs). Here, we report the …

This paper provides the reader with an overview of our current knowledge of hypothalamic‐
pituitary‐thyroid feedback from a cybernetic standpoint. Over the past decades we have …