Transforming growth factor-β (TGF-β) signaling shows important roles in both physiology
and pathology, especially in the progression of inflammatory diseases including cancer …

Dissecting and identifying the major actors and pathways in the genesis, progression and
aggressive advancement of breast cancer is challenging, in part because neoplasms arising …

The overexpression of miR-218-5p in cervical cancer (CC) cell lines decreases migration,
invasion and proliferation. The objective was to identify target genes of miR-218-5p and the …

Background: Breast cancer is the most common malignant tumor in women. RUNX family
has been involved in the regulation of different carcinogenic processes and signaling …

Background Ovarian cancer (OvCa) is a malignant disease of the female reproductive
system with a high mortality rate. LncRNA has been confirmed to play a crucial role in the …

Aim: It remains a challenge to accurately identify malignancy of thyroid nodules when biopsy
is indeterminate. The authors aimed to investigate the abnormal DNA methylation signatures …

Background TGF-beta signaling is a key regulator of immunity and multiple cellular
behaviors in cancer. However, the prognostic and therapeutic role of TGF-beta signaling …

Despite significant progress in the field of human breast cancer research and treatment,
there is a consistent increase in the incidence rate of 0.5 percent annually, posing …

Purpose Transforming growth factor (TGF-β) plays a dual role in tumor progression as well
as a pivotal role in radiation response. TGF-β-related epigenetic regulations, including DNA …

Aquatic viruses can spread rapidly and widely in seawater for their high infective ability.
Polyinosinic-polycytidylic acid (Poly I: C), a viral dsRNA analog, is an immunostimulant that …