Effects of CYP3A4 Variants on Methadone Metabolism In Vitro

C Wang, M Zhang, Y Xu, G Hu, J Cai… - Biomedical …, 2025 - Wiley Online Library
In hepatic drug metabolism, cytochrome P450 (CYP450) enzymes, particularly CYP3A4,
catalyze the majority of drug biotransformations, accounting for over 50% of the CYP450 …

[引用][C] Identification and Functional Assessment of Eight CYP3A4 Allelic Variants* 39–* 46 Detected in the Chinese Han Population

Y Qi, H Yang, S Wang, L Zou, F Zhao, Q Zhang… - Drug Metabolism and …, 2024 - ASPET