The past decade has witnessed exponentially growing interest in the lateral habenula (LHb)
owing to new discoveries relating to its critical role in regulating negatively motivated …

The brain reward circuit has a central role in reinforcing behaviors that are rewarding and
preventing behaviors that lead to punishment. Recent work has shown that the lateral …

The lateral habenula (LH b) is an epithalamic region with a crucial role in the regulation of
midbrain monoaminergic systems. Over the past few years a renewed interest in the LH b …

Most depressed patients suffer from sleep abnormalities, which are one of the critical
symptoms of depression. They are robust risk factors for the initiation and development of …

The ground‐breaking research of patient HM brought to light the importance of the
hippocampus for our memories of everyday and special events. Three quarters of a century …

The lateral habenula (LHb) is part of the habenula complex of the dorsal thalamus. Recent
studies of the LHb have focused on its projections to the ventral tegmental area (VTA) and …

The lateral habenula (LHb) regulates the activity of monoaminergic neurons in the
brainstem. This area has recently attracted a surge of interest in psychiatry because studies …

Serotonergic neurons in the dorsal raphe nucleus (DRN) play an important role in regulation
of many physiological functions. The lateral nucleus of the habenular complex (LHb) is …

Postoperative cognitive dysfunction (POCD) is common and is associated with poor
outcome. Neural circuit involvement in POCD is unknown. Lateral habenula (LHb) that …

Psychiatric disorders with dysfunction of the lateral habenula (LHb) show sleep disturbance,
especially a disinhibition of rapid eye movement (REM) sleep in major depression …