The biological roles of the matrix metalloproteinases (MMPs) have been traditionally
associated with the degradation and turnover of most of the components of the extracellular …

Abstract Follistatin-like 1 (FSTL1) is a secreted glycoprotein displaying expression changes
during development and disease, among which cardiovascular disease, cancer, and …

Epigenetic dysregulation has emerged as an important mechanism in cancer. Alterations in
epigenetic machinery have become a major focus for targeted therapies. The current report …

Myogenic Akt signaling coordinates blood vessel recruitment with normal tissue growth.
Here, we investigated the role of Follistatin-like 1 (Fstl1) in the regulation of endothelial cell …

Background—The Akt protein kinase is an important mediator of cardiac myocyte growth
and survival. To identify factors with novel therapeutic applications in cardiac diseases, we …

Lung morphogenesis is a well orchestrated, tightly regulated process through several
molecular pathways, including TGF-β/bone morphogenetic protein (BMP) signaling …

Matrix metalloproteinases (MMPs) exert both pro-and antiangiogenic functions by the
release of cytokines or proteolytically generated angiogenic inhibitors from extracellular …

Follistatin is an activin-binding protein that prevents activin from binding to its receptors and
neutralizes its activity. Follistatin also binds bone morphogenetic proteins (BMPs). In this …

Purpose: Current methods of classification of astrocytoma based on histopathologic
methods are often subjective and less accurate. Although patients with glioblastoma have …

It is recognized that obesity contributes to cardiovascular and metabolic disorders through
alterations in the levels of adipocyte-derived cytokines (adipokines). Adiponectin is an …