Occlusive thrombosis in arteries

D Kim, C Bresette, Z Liu, DN Ku - APL bioengineering, 2019 - pubs.aip.org
Thrombus formation in major arteries is life threatening. In this review article, we discuss
how an arterial thrombus can form under pathologically high shear stresses, with bonding …

Synthesis of mesoporous CuFe2O4@ SiO2 core-shell nanocomposite for simultaneous drug release and hyperthermia applications

M Talaei, SA Hassanzadeh-Tabrizi, A Saffar-Teluri - Ceramics International, 2021 - Elsevier
In the present work, magnetic CuFe 2 O 4 nanoparticles were synthesized through a sol-gel
combustion. The synthesized CuFe 2 O 4 were coated with mesoporous SiO 2. The …

Mechanical deformation and death of circulating tumor cells in the bloodstream

Y Qiu, T Gao, BR Smith - Cancer and Metastasis Reviews, 2024 - Springer
The circulation of tumor cells through the bloodstream is a significant step in tumor
metastasis. To better understand the metastatic process, circulating tumor cell (CTC) survival …

SIPA in 10 milliseconds: VWF tentacles agglomerate and capture platelets under high shear

ZL Liu, C Bresette, CK Aidun, DN Ku - Blood advances, 2022 - ashpublications.org
Shear-induced platelet aggregation (SIPA) occurs under elevated shear rates (10 000 s− 1)
found in stenotic coronary and carotid arteries. The pathologically high shear environment …

Mechanobiology of shear-induced platelet aggregation leading to occlusive arterial thrombosis: A multiscale in silico analysis

ZL Liu, DN Ku, CK Aidun - Journal of Biomechanics, 2021 - Elsevier
Occlusive thrombosis in arteries causes heart attacks and strokes. The rapid growth of
thrombus at elevated shear rates (~ 10,000 1/s) relies on shear-induced platelet aggregation …

Peristaltic transport of elliptic particles: A numerical study

O Ashtari, M Pourjafar-Chelikdani, K Gharali… - Physics of …, 2022 - pubs.aip.org
Peristaltic transport of elliptic particles suspended in Newtonian fluids is numerically
investigated in a planar channel formed between two flexible membranes. Numerical results …

A numerical study on drug delivery via multiscale synergy of cellular hitchhiking onto red blood cells

M Nikfar, M Razizadeh, R Paul, V Muzykantov, Y Liu - Nanoscale, 2021 - pubs.rsc.org
Red blood cell (RBC)-hitchhiking, in which different nanocarriers (NCs) shuttle on the
erythrocyte membrane and disassociate from RBCs to the first organ downstream of the …

Heterogeneous partition of cellular blood-borne nanoparticles through microvascular bifurcations

ZL Liu, JR Clausen, JL Wagner, KS Butler… - Physical Review E, 2020 - APS
Blood flowing through microvascular bifurcations has been an active research topic for many
decades, while the partitioning pattern of nanoscale solutes in the blood remains relatively …

Quantitative prediction of elongation deformation and shape relaxation of a red blood cell under tensile and shear stresses

C Wu, S Wang, X Qi, W Yan, X Li - Physics of Fluids, 2021 - pubs.aip.org
The characteristic time of stress relaxation is a key viscoelastic property of cell membrane
that controls time-dependent processes such as shape recovery. Although many …

Computational modeling of biomechanics and biorheology of heated red blood cells

ZL Liu, H Li, Y Qiang, P Buffet, M Dao… - Biophysical Journal, 2021 - cell.com
Because of their compromised deformability, heat denatured erythrocytes have been used
as labeled probes to visualize spleen tissue or to assess the ability of the spleen to retain …