The greatest unmet need in multiple sclerosis (MS) are treatments that delay, prevent or
reverse progression. One of the most tractable strategies to achieve this is to therapeutically …

Myelin is the lipid-rich structure formed by oligodendrocytes (OLs) that wraps the axons in
multilayered sheaths, assuring protection, efficient saltatory signal conduction and metabolic …

Current therapeutic landscape in multiple sclerosis: an evol... : Current Opinion in
Neurology Current therapeutic landscape in multiple sclerosis: an evolving treatment …

Biotin is a water‐soluble vitamin that belongs to the vitamin B complex and which is an
essential nutrient of all living organisms from bacteria to man. In eukaryotic cells biotin …

The multiple sclerosis (MS) neurotherapeutic landscape is rapidly evolving. New disease-
modifying therapies (DMTs) with improved efficacy and safety, in addition to an expanding …

Myelin is an essential structure that protects axons, provides metabolic support to neurons
and allows fast nerve transmission. Several neurological diseases, such as multiple …

Objective Retinal nerve fiber layer thickness (RNFL) is a biomarker of neuroaxonal loss and
index of visual function in multiple sclerosis (MS). We aimed to assess the correlation …

Background Multiple sclerosis (MS) is a common demyelinating disease of the central
nervous system. Although the exact pathogenesis remains unknown, the leading theory is …

Background Laboratory tests that use streptavidin–biotin binding mechanisms have the
potential to be affected by high circulating biotin concentrations, which would produce …

Despite the success of disease-modifying treatments in relapsing multiple sclerosis, for
many individuals living with multiple sclerosis, progressive disability continues to accrue …