The dynamic turnover of actin filaments (F-actin) controls cellular motility in eukaryotes and
is coupled to changes in the F-actin nucleotide state,–. It remains unclear how F-actin …

Thymosin β4 (Tβ4) is the β-thymosin (Tβs) with the highest expression level in human cells;
it makes up roughly 70-80% of all Tβs in the human body. Combining the mechanism and …

SLC7A11 plays a pivotal role in tumour development by facilitating cystine import to
enhance glutathione synthesis and counteract oxidative stress. Disulphidptosis, an …

The use of artificial cells to mimic living tissues is beneficial for understanding the
mechanism of interaction among cells. Artificial cells hold immense potential in the field of …

Engineering synthetic cells has a broad appeal, from understanding living cells to designing
novel biomaterials for therapeutics, biosensing, and hybrid interfaces. A key prerequisite to …

Actin filament assembly and the regulation of its mechanical properties are fundamental
processes essential for eukaryotic cell function. Residue E167 in vertebrate actins forms an …

The creation of biologically inspired artificial lipid bilayers on planar supports provides a
unique platform to study membrane-confined processes in a well-controlled setting. At the …

Stereocilia protrude up to 100 µm from the apical surface of vertebrate inner ear hair cells
and are packed with cross-linked filamentous actin (F-actin). They function as mechanical …

Actin plays critical roles in various cellular functions, including cell morphogenesis,
differentiation, and movement. The assembly of actin monomers into double-helical …

Plasmodium actins form very short filaments and have a noncanonical link between ATP
hydrolysis and polymerization. Long filaments are detrimental to the parasites, but the …