Flavonoids as antidiabetic and anti-inflammatory agents: A review on structural activity relationship-based studies and meta-analysis

NF Shamsudin, QU Ahmed, S Mahmood… - International journal of …, 2022 - mdpi.com
Flavonoids are a group of naturally occurring polyphenolic secondary metabolites which
have been reported to demonstrate a wide range of pharmacological properties, most …

Quercetin: a potential polydynamic drug

N Georgiou, MG Kakava, EA Routsi, E Petsas… - Molecules, 2023 - mdpi.com
The study of natural products as potential drug leads has gained tremendous research
interest. Quercetin is one of those natural products. It belongs to the family of flavonoids and …

Anti-malarial and haematological evaluation of the ethanolic, ethyl acetate and aqueous fractions of Chromolaena odorata

TC Elebiyo, OM Oluba, OS Adeyemi - BMC Complementary Medicine and …, 2023 - Springer
Malaria is a global health challenge with endemicity in sub-Saharan Africa, where there are
multiple drug-resistant strains and limited access to modern health care facilities, especially …

Secondary Metabolites Isolated from Artemisia afra and Artemisia annua and Their Anti-Malarial, Anti-Inflammatory and Immunomodulating Properties …

LM Shinyuy, GE Loe, O Jansen, L Mamede, A Ledoux… - Metabolites, 2023 - mdpi.com
There are over 500 species of the genus Artemisia in the Asteraceae family distributed over
the globe, with varying potentials to treat different ailments. Following the isolation of …

Quercetin as a promising antiprotozoan phytochemical: current knowledge and future research avenues

H Memariani, M Memariani… - BioMed Research …, 2024 - Wiley Online Library
Despite tremendous advances in the prevention and treatment of infectious diseases, only
few antiparasitic drugs have been developed to date. Protozoan infections such as malaria …

Natural product-based nanomedicine: Recent advances and issues for the treatment of Alzheimer's disease

CK Woon, WK Hui, R Abas, MH Haron… - Current …, 2022 - benthamdirect.com
Alzheimer's disease (AD) affects the elderly and is characterized by progressive
neurodegeneration caused by different pathologies. The most significant challenges in …

Antimalarial potential of Moringa oleifera Lam. (Moringaceae): A review of the ethnomedicinal, pharmacological, toxicological, and phytochemical evidence

JJL Bezerra, AAV Pinheiro, D Dourado - Journal of Venomous …, 2023 - SciELO Brasil
Several regions of the world frequently use the species Moringa oleifera Lam.(Moringaceae)
in traditional medicine. This situation is even more common in African countries. Many …

Bioactivities and Mode of Actions of Dibutyl Phthalates and Nocardamine from Streptomyces sp. H11809

F Mahmud, NS Lai, SE How, JA Gansau, KMF Mustaffa… - Molecules, 2022 - mdpi.com
Dibutyl phthalate (DBP) produced by Streptomyces sp. H11809 exerted inhibitory activity
against human GSK-3β (Hs GSK-3β) and Plasmodium falciparum 3D7 (Pf 3D7) malaria …

[HTML][HTML] Elucidation of the Active Agents in a West African Ground Herbal Medicine Formulation That Elicit Antimalarial Activities in In Vitro and In Vivo Models

S Owumi, JO Olanlokun, B Wu, AM Duro-Ladipo… - Molecules, 2024 - mdpi.com
Agunmu (ground herbal medicine) is a form of West African traditional medicine consisting
of a cocktail of herbs. The goal of this study is to evaluate a formulation of Agunmu made …

Structure-based virtual screening against multiple Plasmodium falciparum kinases reveals antimalarial compounds

P Godara, KS Reddy, W Sahu, B Naik, V Srivastava… - Molecular Diversity, 2023 - Springer
The continuous emergence of resistance against most frontline antimalarial drugs has led to
countless deaths in malaria-endemic countries, counting 619,000 deaths in 2021, with …