成人肾移植术后血糖控制和CYP3A5 基因多态性对他克莫司谷浓度的影响

李坤, 李璐璐, 李楠楠, 胡卫红… - 中国临床药理学与治疗 …, 2023 - manu41.magtech.com.cn
目的: 糖尿病影响细胞色素P450 3A4/5 (CYP3A4/5) 底物的药代动力学. 因此本研究评估了
血红蛋白A1c (HbA1c) 水平与他克莫司的药代动力学之间的关系. 方法: 回顾性收集肾移植术后 …

Effects of glycaemic control and CYP3A5 polymorphisms on tacrolimus trough concentrations after adult kidney transplantation

K LI, L LI, N LI, W HU, J ZHOU - Chinese Journal of …, 2023 - manu41.magtech.com.cn
AIM: Diabetes mellitus affects the pharmacokinetics of cytochrome P450 3A4/5 (CYP3A4/5)
substrates. We evaluated the relationship between haemoglobin A1c (HbA1c) levels and the …

Development and Validation of a Nomogram for Predicting Subtherapeutic Tacrolimus Blood Levels in Renal Transplant Recipients: A Multivariate Logistic …

B Duan, J Gao, B Ge, S Wu, J Yu - Available at SSRN 4971877 - papers.ssrn.com
This study constructs a nomogram risk prediction model to identify factors affecting
subtherapeutic tacrolimus (FK506) blood concentrations in post-renal transplant patients …