[HTML][HTML] Pathomechanisms in schwannoma development and progression

DL Helbing, A Schulz, H Morrison - Oncogene, 2020 - nature.com
Schwannomas are tumors of the peripheral nervous system, consisting of different cell types.
These include tumorigenic Schwann cells, axons, macrophages, T cells, fibroblasts, blood …

[HTML][HTML] The NLRP3 inflammasome as a target for sensorineural hearing loss

GE Gregory, KJ Munro, KN Couper… - Clinical …, 2023 - Elsevier
Sensorineural hearing loss is the most common type of hearing loss in adults and occurs
due to damage of the inner ear caused by a range of factors including ageing, excessive …

[HTML][HTML] A critical overview of targeted therapies for vestibular schwannoma

R Tamura, M Toda - International journal of molecular sciences, 2022 - mdpi.com
Vestibular schwannoma (VS) is a benign tumor that originates from Schwann cells in the
vestibular component. Surgical treatment for VS has gradually declined over the past few …

[HTML][HTML] The genetic landscape and possible therapeutics of neurofibromatosis type 2

MA Ghalavand, A Asghari, M Farhadi… - Cancer Cell …, 2023 - Springer
Abstract Neurofibromatosis type 2 (NF2) is a genetic condition marked by the development
of multiple benign tumors in the nervous system. The most common tumors associated with …

[HTML][HTML] Sporadic vestibular schwannoma size and location do not correlate with the severity of hearing loss at initial presentation

A Brown, S Early, S Vasilijic, KM Stankovic - Frontiers in oncology, 2022 - frontiersin.org
Vestibular schwannoma (VS) is a non-malignant intracranial neoplasm arising from the
vestibular branch of the 8th cranial nerve; sensorineural hearing loss (SNHL) is the most …

[HTML][HTML] Progression of contralateral hearing loss in patients with sporadic vestibular schwannoma

S Early, CE Rinnooy Kan, M Eggink, JHM Frijns… - Frontiers in …, 2020 - frontiersin.org
Background and Introduction: Vestibular schwannomas (VSs) are the most common tumors
of the cerebellopontine angle, typically presenting unilaterally with ipsilateral sensorineural …

[HTML][HTML] Vestibular schwannoma volume and tumor growth correlates with macrophage marker expression

S Leisz, CH Klause, T Vital Dos Santos, P Haenel… - Cancers, 2022 - mdpi.com
Simple Summary The variable growth behavior of vestibular schwannomas (VS) makes
therapy decisions very difficult. These benign tumors, which originate from the eighth cranial …

[HTML][HTML] Detection of early changes in the post-radiosurgery vestibular schwannoma microenvironment using multinuclear MRI

D Lewis, DJ McHugh, K Li, X Zhu, C Mcbain… - Scientific reports, 2021 - nature.com
Stereotactic radiosurgery (SRS) is an established, effective therapy against vestibular
schwannoma (VS). The mechanisms of tumour response are, however, unknown and in this …

[HTML][HTML] Single-cell RNA sequencing analysis of vestibular schwannoma reveals functionally distinct macrophage subsets

P Baruah, C Mahony, JL Marshall, CG Smith… - British Journal of …, 2024 - nature.com
Abstract Background Vestibular schwannomas (VSs) remain a challenge due to their
anatomical location and propensity to growth. Macrophages are present in VS but their roles …

The SWI/SNF Complex in Neural Crest Cell Development and Disease

DM Fountain, T Sauka-Spengler - Annual Review of Genomics …, 2023 - annualreviews.org
While the neural crest cell population gives rise to an extraordinary array of derivatives,
including elements of the craniofacial skeleton, skin pigmentation, and peripheral nervous …