Off-label use of medication may be presented in these guidelines if a sufficient level of
evidence shows that it can be considered medically appropriate to a given condition and if …

Major haemorrhage is a leading cause of morbidity and mortality worldwide. Successful
treatment requires early recognition, planned responses, readily available resources (such …

Guidelines Management of severe peri-operative bleeding: Guidelines from the European
Society of Anaesthesiology and Intensive Care

Background Major haemorrhage is a clinical emergency that results in morbidity and
mortality: practice guidance is important to reduce these risks. Delayed recognition of …

Myocardial injury is now an acknowledged complication in patients undergoing noncardiac
surgery. Heterogeneity in the definitions of myocardial injury contributes to difficulty in …

Background Compared with anaemia before surgery, the underlying pathogenesis and
implications of postoperative anaemia are largely unknown. Methods This retrospective …

About 300 million adults undergo non-cardiac surgery annually. Although, in this setting, the
incidence of perioperative stroke is low, the absolute number of patients experiencing a …

There are about 310 million major surgical procedures performed each year worldwide, with
more than 4 million deaths within 30 days postoperatively 1. Nearly 8 million surgical …

Tranexamic acid is an antifibrinolytic drug that is widely used during surgery, but there are
concerns about its thromboembolic effects. We aimed to investigate the effect of prophylactic …

Background Postpartum hemorrhage (PPH) is one of the important risk factors leading to
maternal mortality and intervention is essential. Oxytocin therapy is widely used clinically …