Background Different guideline panels, and individuals, may make different decisions based
in part on their preferences. Preferences for or against an intervention are viewed as a …

Background Risk-tailored screening has emerged as a promising approach to optimise the
balance of benefits and harms of existing population cancer screening programs. It tailors …

Background A risk-stratified breast screening program could offer low-risk women less
screening than is currently offered by the National Health Service. The acceptability of this …

Abstract Polygenic Risk Scores (PRS) are statistical methods estimating part of an
individual's genetic susceptibility to various disease phenotypes. Their potential clinical …

Background Today the prerequisites exist to initiate risk-stratified screening according to a
woman's individual risk of breast cancer as opposed to existing one-size-fits-all age-based …

Background Polygenic scores (PGS) have been developed for cancer risk-estimation and
show potential as tools to prompt earlier referral for high-risk individuals and aid risk …

This scoping review aims to systematically gather evidence from personalized cancer-
screening studies across various cancers, summarize key components and outcomes, and …

Introduction. Personalized web-based clinical decision tools for breast cancer prevention
and screening could address knowledge gaps, enhance patient autonomy in shared …

Introduction In response to the critical need for enhancing breast cancer screening for
women with dense breasts, this study explored the understanding of challenges and …

Background. The evidence shows that risk-based strategy could be implemented to avoid
unnecessary harm in mammography screening for breast cancer (BC) using age-only …