MicroRNA in cardiovascular biology and disease.
A Wojciechowska, A Braniewska… - … in Clinical & …, 2017 - search.ebscohost.com
MicroRNAs (miRNAs) are members of a non-coding RNA family. They act as negative
regulators of protein translation by affecting messenger RNA (mRNA) stability; they …
regulators of protein translation by affecting messenger RNA (mRNA) stability; they …
Heart failure 2016: still more questions than answers
Heart failure has reached epidemic proportions given the ageing of populations and is
associated with high mortality and re-hospitalization rates. This article reviews and …
associated with high mortality and re-hospitalization rates. This article reviews and …
Lack of miR-133a decreases contractility of diabetic hearts: a role for novel cross talk between tyrosine aminotransferase and tyrosine hydroxylase
MicroRNAs (miRNAs) have a fundamental role in diabetic heart failure. The cardioprotective
miRNA-133a (miR-133a) is downregulated, and contractility is decreased in diabetic hearts …
miRNA-133a (miR-133a) is downregulated, and contractility is decreased in diabetic hearts …
Regulation of BECN1-mediated autophagy by HSPB6: Insights from a human HSPB6S10F mutant
GS Liu, H Zhu, WF Cai, X Wang, M Jiang, K Essandoh… - Autophagy, 2018 - Taylor & Francis
ABSTRACT HSPB6/Hsp20 (heat shock protein family B [small] member 6) has emerged as a
novel cardioprotector against stress-induced injury. We identified a human mutant of HSPB6 …
novel cardioprotector against stress-induced injury. We identified a human mutant of HSPB6 …
Age‐Dependent Protein Expression of Serine/Threonine Phosphatases and Their Inhibitors in the Human Cardiac Atrium
U Gergs, T Trapp, H Bushnaq, A Simm… - Advances in …, 2019 - Wiley Online Library
Heart failure and aging of the heart show many similarities regarding hemodynamic and
biochemical parameters. There is evidence that heart failure in experimental animals and …
biochemical parameters. There is evidence that heart failure in experimental animals and …
HAX-1 regulates SERCA2a oxidation and degradation
Ischemia/reperfusion injury is associated with contractile dysfunction and increased
cardiomyocyte death. Overexpression of the hematopoietic lineage substrate-1-associated …
cardiomyocyte death. Overexpression of the hematopoietic lineage substrate-1-associated …
Pericardial fluid exosomes: a new material to treat cardiovascular disease
S Sahoo, P Mathiyalagan, RJ Hajjar - Molecular Therapy, 2017 - cell.com
Recent studies using exosomes as a therapeutic platform for the treatment of vascular
diseases have led to very encouraging responses. 1–3 To date, exosomes secreted by stem …
diseases have led to very encouraging responses. 1–3 To date, exosomes secreted by stem …
Role of protein phosphatase inhibitor-1 in cardiac beta adrenergic pathway
S Weber, S Meyer-Roxlau, A El-Armouche - Journal of molecular and …, 2016 - Elsevier
Phosphoproteomic studies have shown that about one third of all cardiac proteins are
reversibly phosphorylated, affecting virtually every cellular signaling pathway. The …
reversibly phosphorylated, affecting virtually every cellular signaling pathway. The …
[HTML][HTML] miR-137 suppresses cell growth and extracellular matrixdegradation through regulating ADAMTS-5 in chondrocytes
Y Zhang, G Wang, L Ma, C Wang, L Wang… - American journal of …, 2019 - ncbi.nlm.nih.gov
Osteoarthritis (OA) is the most common degenerative joint disease. microRNAs (miRNAs)
have been showen to act critical roles in several diseases including OA. However, the …
have been showen to act critical roles in several diseases including OA. However, the …
The roles and mechanisms of epigenetic regulation in pathological myocardial remodeling
K Zhao, Y Mao, Y Li, C Yang, K Wang… - Frontiers in …, 2022 - frontiersin.org
Pathological myocardial remodeling was still one of the leading causes of death worldwide
with an unmet therapeutic need. A growing number of researchers have addressed the role …
with an unmet therapeutic need. A growing number of researchers have addressed the role …