BrdU immunohistochemistry for studying adult neurogenesis: paradigms, pitfalls, limitations, and validation

P Taupin - Brain research reviews, 2007 - Elsevier
Bromodeoxyuridine (BrdU) is a thymidine analog that incorporates DNA of dividing cells
during the S-phase of the cell cycle. As such, BrdU is used for birth dating and monitoring …

Class III β‐tubulin in human development and cancer

CD Katsetos, MM Herman… - Cell motility and the …, 2003 - Wiley Online Library
The differential cellular expression of class III β‐tubulin isotype (βIII) is reviewed in the
context of human embryological development and neoplasia. As compared to somatic …

Adult bone marrow stromal cells differentiate into neural cells in vitro

J Sanchez-Ramos, S Song, F Cardozo-Pelaez… - Experimental …, 2000 - Elsevier
Bone marrow stromal cells (BMSC) normally give rise to bone, cartilage, and mesenchymal
cells. Recently, bone marrow cells have been shown to have the capacity to differentiate into …

Directed migration of neuronal precursors into the ischemic cerebral cortex and striatum

K Jin, Y Sun, L Xie, A Peel, XO Mao, S Batteur… - Molecular and Cellular …, 2003 - Elsevier
Pathological processes, including cerebral ischemia, can enhance neurogenesis in the
adult brain, but the fate of the newborn neurons that are produced and their role in brain …

Effect of mutant α-synuclein on dopamine homeostasis in a new human mesencephalic cell line

J Lotharius, S Barg, P Wiekop, C Lundberg… - Journal of Biological …, 2002 - ASBMB
Mutations in α-synuclein have been linked to rare, autosomal dominant forms of Parkinson's
disease. Despite its ubiquitous expression, mutant α-synuclein primarily leads to the loss of …

Enrichment of neurons and neural precursors from human embryonic stem cells

MK Carpenter, MS Inokuma, J Denham, T Mujtaba… - Experimental …, 2001 - Elsevier
Human embryonic stem (hES) cells proliferate and maintain their pluripotency for over a
year in vitro (M. Amit, MK Carpenter, MS Inokuma, CP Chiu, CP, Harris, MA Waknitz, J …

Human adult stem cells from diverse origins: an overview from multiparametric immunophenotyping to clinical applications

BR Sousa, RC Parreira, EA Fonseca… - Cytometry Part …, 2014 - Wiley Online Library
Stem cells are known for their capacity to self‐renew and differentiate into at least one
specialized cell type. Mesenchymal stem cells (MSCs) were isolated initially from bone …

Class III β-tubulin isotype: a key cytoskeletal protein at the crossroads of developmental neurobiology and tumor neuropathology

CD Katsetos, A Legido, E Perentes… - Journal of child …, 2003 - journals.sagepub.com
The expression of the cytoskeletal protein class III β-tubulin isotype is reviewed in the
context of human central nervous system development and neoplasia. Compared to …

Neural cells derived from adult bone marrow and umbilical cord blood

JR Sanchez‐Ramos - Journal of neuroscience research, 2002 - Wiley Online Library
Under experimental conditions, tissue‐specific stem cells have been shown to give rise to
cell lineages not normally found in the organ or tissue of residence. Neural stem cells from …

Neurogenesis in adult human brain after traumatic brain injury

WM Zheng, Q ZhuGe, M Zhong, G Chen, B Shao… - 2013 - liebertpub.com
While much work has been conducted regarding the neurogenesis response to traumatic
brain injury (TBI) in rodents, it remains largely unknown whether neurogenesis in adult …