Apoptosis is an intrinsic biochemical, cellular process that regulates cell death and is crucial
for cell survival, cellular homeostasis, and maintaining the optimum functional status …

Neuronal death underlies the symptoms of many human neurological disorders, including
Alzheimer's, Parkinson's and Huntington's diseases, stroke, and amyotrophic lateral …

Investigators have long suspected that pathogenic microbes might contribute to the onset
and progression of Alzheimer's disease (AD) although definitive evidence has not been …

This study determined whether retinal degeneration during diabetes includes retinal neural
cell apoptosis. Image analysis of retinal sections from streptozotocin (STZ) diabetic rats after …

Neuronal apoptosis sculpts the developing brain and has a potentially important role in
neurodegenerative diseases. The principal molecular components of the apoptosis …

Parkinson's disease (PD) is a neurodegenerative disorder characterized by progressive cell
loss confined mostly to dopaminergic neurons of the substantia nigra. Several factors …

Circulating cell-free RNA in the blood provides a potential window into the health,
phenotype, and developmental programs of a variety of human organs. We used high …

Recent advances in defining the molecular signaling pathways that regulate the
phagocytosis of apoptotic cells have improved our understanding of this complex and …

Caspases are a family of cysteinyl aspartate-specific proteases that are highly conserved in
multicellular organisms and function as central regulators of apoptosis. A member of this …

beta-Amyloid precursor protein (beta-APP), the source of the fibrillogenic amyloid beta-
peptide (A beta) that accumulates in the brain of victims of Alzheimer's disease, is a …