Brain, the major organ of the central nervous system controls and processes most of body
activities. Therefore, the most aggressive brain tumor–glioblastoma and metastases from …

Background. Glioblastoma is the most frequent and aggressive brain tumour in humans with
median survival from 12 to 15 months after the diagnosis. This is mostly due to therapy …

Exosomes contain plenty of bioactive information, playing an important role in intercellular
communication by transfer their bioactive molecular contents to recipient cells. Glioblastoma …

The average survival of patients with glioblastoma is 12–15 months. Therefore, finding a
new treatment method is important, especially in cases that show resistance to treatment …

The chemokine CCL5/RANTES is a versatile inflammatory mediator, which interacts with the
receptor CCR5, promoting cancer cell interactions within the tumor microenvironment …

Glioblastoma multiforme are an aggressive form of brain tumors that are characterized by
distinct invasion of single glioblastoma cells, which infiltrate the brain parenchyma. This …

Due to their superb light absorption and photostability conjugated polymer nanoparticles are
promising photosensitizers (PS) for their use in Photodynamic therapy (PDT). Recently, we …

Extra-domain B of fibronectin (EDB-FN) is an alternatively spliced form of fibronectin with
high expression in the extracellular matrix of neovascularized tissues and malignant cancer …

LRP1B remains one of the most altered genes in cancer, although its relevance in cancer
biology is still unclear. Recent advances in gene editing techniques, particularly …

Photodynamic therapy (PDT) has recently gained attention as an alternative treatment of
malignant gliomas. Glioblastoma (GBM) is the most prevalent within tumors of the central …