Growing evidence suggests an increasing significance for the extent of gastrointestinal tract
(GIT) dysfunction in Parkinson's disease (PD). Most patients suffer from GIT symptoms …

The glial cell of the peripheral nervous system (PNS), the Schwann cell (SC), counts among
the most multifaceted cells of the body. During development, SCs secure neuronal survival …

Development of the human intestine is not well understood. Here, we link single-cell RNA
sequencing and spatial transcriptomics to characterize intestinal morphogenesis through …

Background The intestinal microbiota plays an important role in regulating gastrointestinal
(GI) physiology in part through interactions with the enteric nervous system (ENS) …

Traumatic brain injury (TBI) is a chronic and progressive disease, and management requires
an understanding of both the primary neurological injury and the secondary sequelae that …

The enteric nervous system (ENS) is the largest division of the peripheral nervous system
and closely resembles components and functions of the central nervous system. Although …

It has become increasingly evident in recent years that the gut microbiome and the brain
communicate in a bidirectional manner, with each possibly affecting the other's functions …

Glial fibrillary acidic protein (GFAP) is an intermediate filament (IF) III protein uniquely found
in astrocytes in the central nervous system (CNS), non-myelinating Schwann cells in the …

A complex bidirectional communication system exists between the gastrointestinal tract and
the brain. Initially termed the “gut-brain axis” it is now renamed the “microbiota-gut-brain …

The high turnover and regenerative capacity of the adult intestine relies on resident stem
cells located at the bottom of the crypt. The enteric nervous system consists of an abundant …