The cardiovascular system: mathematical modelling, numerical algorithms and clinical applications

A Quarteroni, A Manzoni, C Vergara - Acta Numerica, 2017 - cambridge.org
Mathematical and numerical modelling of the cardiovascular system is a research topic that
has attracted remarkable interest from the mathematical community because of its intrinsic …

Computational modeling of cardiac hemodynamics: current status and future outlook

R Mittal, JH Seo, V Vedula, YJ Choi, H Liu… - Journal of …, 2016 - Elsevier
The proliferation of four-dimensional imaging technologies, increasing computational
speeds, improved simulation algorithms, and the widespread availability of powerful …

Integrated heart—coupling multiscale and multiphysics models for the simulation of the cardiac function

A Quarteroni, T Lassila, S Rossi… - Computer Methods in …, 2017 - Elsevier
Mathematical modeling of the human heart and its function can expand our understanding of
various cardiac diseases, which remain the most common cause of death in the developed …

A mathematical model that integrates cardiac electrophysiology, mechanics, and fluid dynamics: Application to the human left heart

M Bucelli, A Zingaro, PC Africa… - … journal for numerical …, 2023 - Wiley Online Library
We propose a mathematical and numerical model for the simulation of the heart function that
couples cardiac electrophysiology, active and passive mechanics and hemodynamics, and …

[图书][B] Mathematical modelling of the human cardiovascular system: data, numerical approximation, clinical applications

A Quarteroni, A Manzoni, C Vergara - 2019 - books.google.com
Mathematical and numerical modelling of the human cardiovascular system has attracted
remarkable research interest due to its intrinsic mathematical difficulty and the increasing …

Heart blood flow simulation: a perspective review

SN Doost, D Ghista, B Su, L Zhong… - Biomedical engineering …, 2016 - Springer
Cardiovascular disease (CVD), the leading cause of death today, incorporates a wide range
of cardiovascular system malfunctions that affect heart functionality. It is believed that the …

Application of patient-specific computational fluid dynamics in coronary and intra-cardiac flow simulations: Challenges and opportunities

L Zhong, JM Zhang, B Su, RS Tan, JC Allen… - Frontiers in …, 2018 - frontiersin.org
The emergence of new cardiac diagnostics and therapeutics of the heart has given rise to
the challenging field of virtual design and testing of technologies in a patient-specific …

Computational fluid dynamic analysis of the left atrial appendage to predict thrombosis risk

GM Bosi, A Cook, R Rai, LJ Menezes… - Frontiers in …, 2018 - frontiersin.org
During Atrial Fibrillation (AF) more than 90% of the left atrial thrombi responsible for
thromboembolic events originate in the left atrial appendage (LAA), a complex small sac …

lifex-cfd: An open-source computational fluid dynamics solver for cardiovascular applications

PC Africa, I Fumagalli, M Bucelli, A Zingaro… - Computer Physics …, 2024 - Elsevier
Computational fluid dynamics (CFD) is an important tool for the simulation of the
cardiovascular function and dysfunction. Due to the complexity of the anatomy, the …

Fluid mechanics of heart valves and their replacements

F Sotiropoulos, TB Le, A Gilmanov - Annual Review of Fluid …, 2016 - annualreviews.org
As the pulsatile cardiac blood flow drives the heart valve leaflets to open and close, the flow
in the vicinity of the valve resembles a pulsed jet through a nonaxisymmetric orifice with a …